From organophosphate poisoning to diabetes mellitus: The incretin effect
Rathish D, Agampodi SB, Jayasumana MACS, Siribaddana SH. From organophosphate poisoning to diabetes mellitus: The incretin effect. Medical Hypotheses 2016, 91: 53-55. PMID: 27142144, DOI: 10.1016/j.mehy.2016.04.002.Peer-Reviewed Original ResearchConceptsAccumulation of acetylcholineIncretin effectGlucose homeostasisDiabetes mellitusOP poisoningType 2 diabetes mellitusPeptide-1 secretionAcute OPMuscarinic receptorsTreatment modalitiesOrganophosphate poisoningPositive findingsInhibition of acetylcholinesterasesMellitusInduced disruptionHomeostasisPoisoningInhibitionDisruptionT2DMAcetylcholineGlucagonIncidenceSecretionReceptors