1993
Domain 5 interacts with domain 6 and influences the second transesterification reaction of group II intron self-splicing
Dib-Hajj S, Boulanger S, Hebbar S, Peebles C, Franzen J, Perlman P. Domain 5 interacts with domain 6 and influences the second transesterification reaction of group II intron self-splicing. Nucleic Acids Research 1993, 21: 1797-1804. PMID: 8493099, PMCID: PMC309417, DOI: 10.1093/nar/21.8.1797.Peer-Reviewed Original ResearchConceptsSplice site useSplice site utilizationSplice siteDomain 5Yeast mitochondrial DNAGroup II intronsSecond transesterification reactionSubstrate transcriptsCoxI geneSplicing occursMitochondrial DNARNA moleculesDomain 6RNAExonsD5 RNASite utilizationTranscriptsKey roleIntronsBranchingSite residentsSite useGenesSites
1992
Group II introns deleted for multiple substructures retain self-splicing activity.
Koch J, Boulanger S, Dib-Hajj S, Hebbar S, Perlman P. Group II introns deleted for multiple substructures retain self-splicing activity. Molecular And Cellular Biology 1992, 12: 1950-1958. PMID: 1569932, PMCID: PMC364365, DOI: 10.1128/mcb.12.5.1950.Peer-Reviewed Original ResearchConceptsGroup II intronsSplice site selectionSelf-splicing activitySplice junctionsDomain 2Domain 5Domain 1Essential catalytic coreYeast mitochondrial DNASecondary structure elementsCoxI geneSelf-splicing reactionMitochondrial DNAPrecursor RNAMutant intronsCatalytic coreIntron domainsTriple deletionIntronsTrans assaySingle deletionSecondary structureDomain 6DeletionStructure elementsGroup II Introns Deleted for Multiple Substructures Retain Self-Splicing Activity
Koch J, Boulanger S, Dib-Hajj S, Hebbar S, Perlman P. Group II Introns Deleted for Multiple Substructures Retain Self-Splicing Activity. Molecular And Cellular Biology 1992, 12: 1950-1958. DOI: 10.1128/mcb.12.5.1950-1958.1992.Peer-Reviewed Original ResearchGroup II intronsSplice site selectionSplice junctionsDomain 2Domain 5Domain 1Essential catalytic coreYeast mitochondrial DNASelf-splicing activitySecondary structure elementsCoxI geneSelf-splicing reactionMitochondrial DNAPrecursor RNAMutant intronsCatalytic coreIntron domainsTriple deletionTrans assayIntronsSingle deletionSecondary structureDomain 6DeletionStructure elements