1999
Coding Sequence, Genomic Organization, and Conserved Chromosomal Localization of the Mouse Gene Scn11a Encoding the Sodium Channel NaN
Dib-Hajj S, Tyrrell L, Escayg A, Wood P, Meisler M, Waxman S. Coding Sequence, Genomic Organization, and Conserved Chromosomal Localization of the Mouse Gene Scn11a Encoding the Sodium Channel NaN. Genomics 1999, 59: 309-318. PMID: 10444332, DOI: 10.1006/geno.1999.5890.Peer-Reviewed Original ResearchConceptsSodium channel geneChannel genesConserved linkage groupMouse chromosome 9Sodium channel alphaAlternative exon 5Amino acid levelsGenomic organizationChromosomal localizationLinkage groupsHuman genesHuman SCN5ACoding sequenceCommon lineageChannel alphaChromosome 9TTX-R sodium channelsGenesSmall-diameter sensory neuronsTransduction of painDorsal root gangliaHigh-threshold nociceptorsExon 5SCN11A geneSodium channels
1997
Schwann cells modulate sodium channel expression in spinal sensory neurons in vitro
Hinson AW, Gu XQ, Dib‐Hajj S, Black JA, Waxman SG. Schwann cells modulate sodium channel expression in spinal sensory neurons in vitro. Glia 1997, 21: 339-349. PMID: 9419009, DOI: 10.1002/(sici)1098-1136(199712)21:4<339::aid-glia1>3.0.co;2-z.Peer-Reviewed Original ResearchConceptsDRG neuronsSC-conditioned mediumSodium channel alphaE15 ratsSodium channelsChannel alphaSodium channel immunoreactivitySpinal sensory neuronsBeta2 subunit mRNASodium channel mRNASodium channel expressionFunctional sodium channelsSodium current densityBeta-subunit mRNAChannel immunoreactivityBeta2 mRNASensory neuronsClamp recordingsChannel expressionChannel mRNAIsoform-specific riboprobesNeuronsBeta1RatsHybridization signals