Experimental approaches to the development of a recombinant hookworm vaccine
Hotez P, Ghosh K, Huwdon J, Narasimhan S, Jones B, Shuhua X, Sen L, Bin Z, Haechou X, Hainan R, Heng W, Koski R. Experimental approaches to the development of a recombinant hookworm vaccine. Immunological Reviews 1999, 171: 163-171. PMID: 10582170, DOI: 10.1111/j.1600-065x.1999.tb01347.x.Peer-Reviewed Original ResearchConceptsHookworm infectionHeavy hookworm infectionMajor parasitic causeHookworm antigensSerologic correlatesVaccine protectionChallenge infectionHookworm burdenHookworm vaccineParasitic causesEndemic areasHuman infectionsInfectionLaboratory animalsVaccineAlum precipitateMorbidityRecombinant polypeptidesHookwormAntigenDiseaseMiceImmunityAntibodies