2020
Association of SLC1A1 Gene Polymorphism With Obsessive Compulsive Disorder in a Sample From Southern India
Shukla T, Nadella R, J. R, Ganesh S, Nestadt G, Purushottam M, Jain S, Reddy Y, Viswanath B. Association of SLC1A1 Gene Polymorphism With Obsessive Compulsive Disorder in a Sample From Southern India. Experimental And Clinical Psychopharmacology 2020, 28: 617-621. PMID: 31985241, DOI: 10.1037/pha0000348.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderTreatment responseAge of onsetSRI treatment responseSignificant associationClinical parametersMini International Neuropsychiatric InterviewGenotype/allele frequenciesSymptom dimensionsSpecialty OCD clinicAdequate trialFull respondersNeuropsychiatric InterviewHealthy controlsBrain volumeGene polymorphismsOCD clinicDisease severityCase-control association analysisSymptom severityOCD patientsOCD casesGenotype frequenciesCompulsive disorderAssociationAdverse childhood experiences in families with multiple members diagnosed to have psychiatric illnesses
Someshwar A, Holla B, Pansari Agarwal P, Thomas A, Jose A, Joseph B, Raju B, Karle H, Muthukumaran M, Kodancha P, Kumar P, Reddy P, Kumar Nadella R, Naik S, Mitra S, Mallappagiri S, Sreeraj V, Balachander S, Ganesh S, Murthy P, Benegal V, Reddy J, Jain S, Mahadevan J, Viswanath B, Rao N, Narayanaswamy J, Sivakumar P, Kandasamy A, Kesavan M, Mehta U, Venkatasubramanian G, John J, Mukherjee O, Purushottam M, Kannan R, Mehta B, Kandavel T, Binukumar B, Saini J, Jayarajan D, Shyamsundar A, Moirangthem S, Vijay Kumar K, Thirthalli J, Chandra P, Gangadhar B, Panicker M, Bhalla U, Chattarji S, Varghese M, Raghu P, Rao M. Adverse childhood experiences in families with multiple members diagnosed to have psychiatric illnesses. Australian & New Zealand Journal Of Psychiatry 2020, 54: 1086-1094. PMID: 32538179, DOI: 10.1177/0004867420931157.Peer-Reviewed Original ResearchConceptsFirst-degree relativesAdverse childhood experience exposureMajor psychiatric conditionsAdverse childhood experiencesObsessive-compulsive disorderSeverity scorePsychiatric conditionsSubstance dependencePsychiatric illnessBipolar disorderAdverse Childhood Experiences International QuestionnaireRisk first-degree relativesChildhood experiencesCo-occurring diagnosesAge of onsetEarly ageInteraction of diagnosisOngoing longitudinal studyPsychiatric diagnosis
2017
BDNF gene and obsessive compulsive disorder risk, symptom dimensions and treatment response
J R, Ganesh S, Shukla T, Deolankar S, Nadella R, Sen S, Purushottam M, Reddy Y, Jain S, Viswanath B. BDNF gene and obsessive compulsive disorder risk, symptom dimensions and treatment response. Asian Journal Of Psychiatry 2017, 38: 65-69. PMID: 29079096, DOI: 10.1016/j.ajp.2017.10.014.Peer-Reviewed Original Research