2022
How metal augments, polyethylene thickness and stem length affect tibial baseplate load transfer in revision total knee arthroplasty
LaMonica J, Pham N, Milligan K, Tommasini S, Schwarzkopf R, Parisi R, Wiznia D. How metal augments, polyethylene thickness and stem length affect tibial baseplate load transfer in revision total knee arthroplasty. The Knee 2022, 40: 283-291. PMID: 36529046, DOI: 10.1016/j.knee.2022.11.021.Peer-Reviewed Original Research
2016
Novel anatomic adaptation of cortical bone to meet increased mineral demands of reproduction
Macica CM, King HE, Wang M, McEachon CL, Skinner CW, Tommasini SM. Novel anatomic adaptation of cortical bone to meet increased mineral demands of reproduction. Bone 2016, 85: 59-69. PMID: 26825813, PMCID: PMC7429445, DOI: 10.1016/j.bone.2015.12.056.Peer-Reviewed Original ResearchConceptsHyp miceMineral homeostasisElevated serum PTHMaternal bone massMineralized trabecular boneIntestinal calcium absorptionCortical boneWild-type miceSerum PTHCalcitriol productionFemale patientsMaternal skeletonPostnatal nutritionCalcium absorptionBone resorptionFracture riskMaternal adaptationBone massBone fragilityMurine modelIntracortical porosityUnaffected miceMouse modelMMP-13Fetal development
2014
Periosteal PTHrP regulates cortical bone modeling during linear growth in mice
Wang M, VanHouten JN, Nasiri AR, Tommasini SM, Broadus AE. Periosteal PTHrP regulates cortical bone modeling during linear growth in mice. Journal Of Anatomy 2014, 225: 71-82. PMID: 24762197, PMCID: PMC4073294, DOI: 10.1111/joa.12184.Peer-Reviewed Original ResearchConceptsMetaphyseal-diaphyseal junctionParathyroid hormone-related peptideEndocortical bone formationCD-1 miceNF-kB ligandHormone-related peptideMineral apposition rateCortical bone modelingEntire boneLinear growthAnteromedial cortexCKO miceProximal tibiaLateral tibiaReceptor activatorOC numberApposition rateOsteoclastic resorptionPTHrPBone modelingBone formationFibulaLong bonesMicePeriosteum
2008
Biological Co‐Adaptation of Morphological and Composition Traits Contributes to Mechanical Functionality and Skeletal Fragility1*
Tommasini SM, Nasser P, Hu B, Jepsen KJ. Biological Co‐Adaptation of Morphological and Composition Traits Contributes to Mechanical Functionality and Skeletal Fragility1*. Journal Of Bone And Mineral Research 2008, 23: 236-246. PMID: 17922614, PMCID: PMC2665697, DOI: 10.1359/jbmr.071014.Peer-Reviewed Original Research
2006
Sexual dimorphism affects tibia size and shape but not tissue-level mechanical properties
Tommasini SM, Nasser P, Jepsen KJ. Sexual dimorphism affects tibia size and shape but not tissue-level mechanical properties. Bone 2006, 40: 498-505. PMID: 17035111, DOI: 10.1016/j.bone.2006.08.012.Peer-Reviewed Original Research
2005
Relationship Between Bone Morphology and Bone Quality in Male Tibias: Implications for Stress Fracture Risk*
Tommasini SM, Nasser P, Schaffler MB, Jepsen KJ. Relationship Between Bone Morphology and Bone Quality in Male Tibias: Implications for Stress Fracture Risk*. Journal Of Bone And Mineral Research 2005, 20: 1372-1380. PMID: 16007335, DOI: 10.1359/jbmr.050326.Peer-Reviewed Original ResearchConceptsStress fracture riskYears of ageFracture riskBone sizeTissue-level mechanical propertiesStress fracturesNew prevention strategiesMale military recruitsBone morphologySlender bonesMedial-lateral widthNarrower tibiaeFracture incidenceBone quality parametersMales 17Tissue fragilityTibial diaphysisAnimal modelsBody weightPrevention strategiesBone qualityMilitary recruitsSection modulusCortical tissueMale athletes