Lead induced differences in bone properties in osteocalcin +/+ and −/− female mice
Yildirim G, Budell W, Berezovska O, Yagerman S, Maliath S, Mastrokostas P, Tommasini S, Dowd T. Lead induced differences in bone properties in osteocalcin +/+ and −/− female mice. Bone Reports 2023, 18: 101672. PMID: 37064000, PMCID: PMC10090701, DOI: 10.1016/j.bonr.2023.101672.Peer-Reviewed Original ResearchBone strengthMineral/matrixBone remodelingHigher blood lead levelsSerum turnover markersLow lead exposureMajor health problemBlood lead levelsRole of osteocalcinBV/TVBone mineral propertiesTurnover markersFracture riskFemale miceLead exposureHealth problemsEffects of leadLead levelsBone formationCollagen maturityCross-sectional areaOsteocalcinLead toxicityBone propertiesBiomechanical measurements