2023
Lead induced differences in bone properties in osteocalcin +/+ and −/− female mice
Yildirim G, Budell W, Berezovska O, Yagerman S, Maliath S, Mastrokostas P, Tommasini S, Dowd T. Lead induced differences in bone properties in osteocalcin +/+ and −/− female mice. Bone Reports 2023, 18: 101672. PMID: 37064000, PMCID: PMC10090701, DOI: 10.1016/j.bonr.2023.101672.Peer-Reviewed Original ResearchBone strengthMineral/matrixBone remodelingHigher blood lead levelsSerum turnover markersLow lead exposureMajor health problemBlood lead levelsRole of osteocalcinBV/TVBone mineral propertiesTurnover markersFracture riskFemale miceLead exposureHealth problemsEffects of leadLead levelsBone formationCollagen maturityCross-sectional areaOsteocalcinLead toxicityBone propertiesBiomechanical measurements
2018
Human Amniotic Membrane Improves Healing in a Chronic, Massive Rotator Cuff Repair Model
Kovacevic D, Suriani R, Saad M, Tommasini S, Mendias C, Carroll C, Blaine T. Human Amniotic Membrane Improves Healing in a Chronic, Massive Rotator Cuff Repair Model. Orthopaedic Journal Of Sports Medicine 2018, 6: 2325967118s00167. PMCID: PMC6102762, DOI: 10.1177/2325967118s00167.Peer-Reviewed Original ResearchTendon-bone interfaceRotator cuff injuryHuman amniotic membraneER groupAmniotic membraneCuff injuryChronic injuryLipid depositionCross-sectional areaMuscle fiber forcePAI-1Male Sprague-Dawley ratsRepair gene expressionBone formationPlasminogen activator inhibitor-1 expressionRotator cuff tendon–bone healingTransosseous suture fixationRepair siteRotator cuff repair modelMuscle fibersTendon-bone healingSprague-Dawley ratsRotator cuff musclesLess PAI-1Real-time polymerase chain reaction