2023
Neonatal Paenibacilliosis: Paenibacillus Infection as a Novel Cause of Sepsis in Term Neonates With High Risk of Sequelae in Uganda
Ericson J, Burgoine K, Kumbakumba E, Ochora M, Hehnly C, Bajunirwe F, Bazira J, Fronterre C, Hagmann C, Kulkarni A, Kumar M, Magombe J, Mbabazi-Kabachelor E, Morton S, Movassagh M, Mugamba J, Mulondo R, Natukwatsa D, Kaaya B, Olupot-Olupot P, Onen J, Sheldon K, Smith J, Ssentongo P, Ssenyonga P, Warf B, Wegoye E, Zhang L, Kiwanuka J, Paulson J, Broach J, Schiff S. Neonatal Paenibacilliosis: Paenibacillus Infection as a Novel Cause of Sepsis in Term Neonates With High Risk of Sequelae in Uganda. Clinical Infectious Diseases 2023, 77: 768-775. PMID: 37279589, PMCID: PMC10495130, DOI: 10.1093/cid/ciad337.Peer-Reviewed Original ResearchConceptsNeonatal sepsisPostinfectious hydrocephalusCerebrospinal fluidSigns of sepsisFull-term neonatesOptimal antibiotic treatmentUgandan referral hospitalQuantitative polymerase chain reactionNeonatal characteristicsClinical sepsisTerm neonatesUnderdiagnosed causeAntibiotic choiceMedian ageReferral hospitalUgandan hospitalNeurodevelopmental impairmentAdverse outcomesSpecimen typesAntibiotic treatmentPolymerase chain reactionClinical signsUnusual pathogensSepsisHigh risk
2011
Association of bacteria with hydrocephalus in Ugandan infants.
Li L, Padhi A, Ranjeva S, Donaldson S, Warf B, Mugamba J, Johnson D, Opio Z, Jayarao B, Kapur V, Poss M, Schiff S. Association of bacteria with hydrocephalus in Ugandan infants. Journal Of Neurosurgery Pediatrics 2011, 7: 73-87. PMID: 21194290, DOI: 10.3171/2010.9.peds10162.Peer-Reviewed Original ResearchConceptsUgandan infantsNeonatal sepsisPostinfectious hydrocephalusMajority of patientsMost patientsRecent infectionPolymerase chain reactionEffective treatmentPatientsPrevention strategiesHydrocephalusInfectionInfantsAcinetobacter speciesChain reactionAssociation of bacteriaBacterial DNAGram-negative bacteriaNegative bacteriaSepsisEnvironmental samplingSyndromeSeason infection