2011
Maropitant citrate for treatment of ulcerative dermatitis in mice with a C57BL/6 background.
Williams-Fritze MJ, Carlson Scholz JA, Zeiss C, Deng Y, Wilson SR, Franklin R, Smith PC. Maropitant citrate for treatment of ulcerative dermatitis in mice with a C57BL/6 background. Journal Of The American Association For Laboratory Animal Science 2011, 50: 221-6. PMID: 21439216, PMCID: PMC3061423.Peer-Reviewed Original ResearchConceptsMaropitant citrateSubstance PUlcerative dermatitisC57BL/6 backgroundInhibition of SPCommon progressive conditionItch-scratch cycleNK1 receptor antagonistNeurokinin-1 receptorTachykinin neurokinin-1 receptorUD lesionsItch sensationExact etiologyInflamed skinReceptor antagonistNK1 receptorsProgressive conditionDorsal neckSkin traumaAdditional traumaTherapeutic interventionsImportant neuropeptideMiceDermatitisLesions
2008
Intranasal immunization with recombinant vesicular stomatitis virus expressing murine cytomegalovirus glycoprotein B induces humoral and cellular immunity.
Wilson SR, Wilson JH, Buonocore L, Palin A, Rose JK, Reuter JD. Intranasal immunization with recombinant vesicular stomatitis virus expressing murine cytomegalovirus glycoprotein B induces humoral and cellular immunity. Comparative Medicine 2008, 58: 129-39. PMID: 18524170, PMCID: PMC2703170.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, IntranasalAnimalsAntibody FormationCD8-Positive T-LymphocytesDNA, RecombinantDNA, ViralFemaleHerpesviridae InfectionsImmunity, CellularImmunizationInterferon-gammaMaleMiceMice, Inbred C57BLMuromegalovirusNeutralization TestsSpecific Pathogen-Free OrganismsSpleenVesiculovirusViral Envelope ProteinsViral VaccinesConceptsRecombinant vesicular stomatitis virusMurine cytomegalovirusIntranasal immunizationCellular immunityVesicular stomatitis virusSingle intranasal vaccinationStomatitis virusValuable animal modelIntranasal vaccinationMucosal vaccinationImmunized miceVaccine strategiesIFNgamma responsesVaccine prophylaxisCell surface expressionLeading causeImmune responseMouse modelVaccine vectorLive virusAnimal modelsViral infectionStrong cytoplasmicMajor envelope proteinSurface expression
2005
The Beta-1 Adrenergic Antagonist, Betaxolol, Improves Working Memory Performance in Rats and Monkeys
Ramos BP, Colgan L, Nou E, Ovadia S, Wilson SR, Arnsten AF. The Beta-1 Adrenergic Antagonist, Betaxolol, Improves Working Memory Performance in Rats and Monkeys. Biological Psychiatry 2005, 58: 894-900. PMID: 16043136, DOI: 10.1016/j.biopsych.2005.05.022.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-1 Receptor AntagonistsAdrenergic beta-AntagonistsAnimalsAttentionBetaxololCognitionDose-Response Relationship, DrugHypnotics and SedativesMacaca mulattaMaleMaze LearningMemory, Short-TermMicroinjectionsPancreatic DiseasesPrefrontal CortexPsychomotor PerformanceRatsStereotaxic TechniquesConceptsMemory performancePrefrontal cortexPost-traumatic stress disorderPFC cognitive functionCognitive functioningStress disorderAlternation testingCognitive functionPFC functionBeta-1 adrenergic antagonistBeta 2 receptorsPFC dysfunctionPancreatic side effectsPFC infusionAged monkeysNoradrenergic activityCurrent studySelective beta 1 antagonistDose-related improvementBeta 1Beta 1/betaBeta-adrenergic receptor stimulationBeta-1 antagonistAdrenergic receptor stimulationWarrants further investigationSuccessful cyclosporine treatment for atopic dermatitis in a rhesus macaque (Macaca mulatta).
Ovadia S, Wilson SR, Zeiss CJ. Successful cyclosporine treatment for atopic dermatitis in a rhesus macaque (Macaca mulatta). Comparative Medicine 2005, 55: 192-6. PMID: 15884783.Peer-Reviewed Original ResearchConceptsAtopic dermatitisSkin conditionsRhesus macaquesMonths of treatmentHistory of allergyInflammatory skin conditionFemale rhesus macaquesSuccessful therapeutic agentsCyclosporine treatmentOral cyclosporineImmunological injuryCalcineurin inhibitorsChronic courseImmunomodulatory drugsMetabolic abnormalitiesClinical evidenceLymphocyte functionSuccessful treatmentComplete hemogramDifferential diagnosisNormal limitsSuccessful therapyInguinal regionAllergic dermatitisDistal extremities