2008
Crystal structure of the λ repressor and a model for pairwise cooperative operator binding
Stayrook S, Jaru-Ampornpan P, Ni J, Hochschild A, Lewis M. Crystal structure of the λ repressor and a model for pairwise cooperative operator binding. Nature 2008, 452: 1022-1025. PMID: 18432246, DOI: 10.1038/nature06831.Peer-Reviewed Original Research
2006
The Structural Basis of Cooperative Regulation at an Alternate Genetic Switch
Pinkett H, Shearwin K, Stayrook S, Dodd I, Burr T, Hochschild A, Egan J, Lewis M. The Structural Basis of Cooperative Regulation at an Alternate Genetic Switch. Molecular Cell 2006, 21: 605-615. PMID: 16507359, DOI: 10.1016/j.molcel.2006.01.019.Peer-Reviewed Original ResearchConceptsGenetic switchC-terminal domainTemperate bacteriophagesCooperativity mutantsBacteriophage lambdaGene regulationRegulatory regionsRepressor monomersGenetic screeningGenetic studiesMolecular basisRepressorStructural basisRegulatory activityBacteriophageCooperative regulationRegulationLambdaMutantsGenesTemperate