2018
Efficacy of Extended-Release Naltrexone on HIV-Related and Drinking Outcomes Among HIV-Positive Patients: A Randomized-Controlled Trial
Edelman EJ, Moore BA, Holt SR, Hansen N, Kyriakides TC, Virata M, Brown ST, Justice AC, Bryant KJ, Fiellin DA, Fiellin LE. Efficacy of Extended-Release Naltrexone on HIV-Related and Drinking Outcomes Among HIV-Positive Patients: A Randomized-Controlled Trial. AIDS And Behavior 2018, 23: 211-221. PMID: 30073637, PMCID: PMC6476298, DOI: 10.1007/s10461-018-2241-z.Peer-Reviewed Original ResearchConceptsHIV-positive patientsHeavy drinking daysVACS Index scoreXR-NTXART adherenceDrinking daysIndex scoreUndetectable HIV viral loadCD4 cell countExtended-release naltrexoneDouble-blind placeboHIV viral loadRandomized-controlled trialDrinking outcomesHIV biomarkersSecondary outcomesHIV outcomesPrimary outcomeViral loadAntiretroviral adherenceClinical trialsCell countAlcohol treatmentHIVPatientsPharmacotherapy for Alcohol Use Disorder
Holt SR, Tobin DG. Pharmacotherapy for Alcohol Use Disorder. Medical Clinics Of North America 2018, 102: 653-666. PMID: 29933821, DOI: 10.1016/j.mcna.2018.02.008.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAlcohol use disorderUse disordersNondrug therapiesUndertreated diseaseTreatment optionsPharmacotherapeutic agentsDrug interactionsTreatment goalsUS FoodDrug AdministrationSpecific patientDrug availabilityDisordersPatientsCounseling strategiesComorbiditiesMedicationsPharmacotherapyOptionsTherapyDiseaseAdministrationCare
2016
Caring for patients with opioid use disorder in the hospitalCaring for patients with opioid use disorder in the hospital
Donroe JH, Holt SR, Tetrault JM. Caring for patients with opioid use disorder in the hospitalCaring for patients with opioid use disorder in the hospital. Canadian Medical Association Journal 2016, 188: cmaj.160290. PMID: 27647616, PMCID: PMC5135493, DOI: 10.1503/cmaj.160290.Peer-Reviewed Original Research