2019
Repeated semen exposure decreases cervicovaginal SIVmac251 infection in rhesus macaques
Abdulhaqq S, Martinez M, Kang G, Rodriguez I, Nichols S, Beaumont D, Joseph J, Azzoni L, Yin X, Wise M, Weiner D, Liu Q, Foulkes A, Münch J, Kirchhoff F, Coutifaris C, Tomaras G, Sariol C, Marx P, Li Q, Kraiselburd E, Montaner L. Repeated semen exposure decreases cervicovaginal SIVmac251 infection in rhesus macaques. Nature Communications 2019, 10: 3753. PMID: 31434895, PMCID: PMC6704120, DOI: 10.1038/s41467-019-11814-5.Peer-Reviewed Original ResearchConceptsCD4+ T cellsFemale reproductive tractSemen exposureT cellsIncreased infiltration of CD4+ T cellsMale-to-female HIV transmissionCirculating CD4+ T cellsInfiltration of CD4+ T cellsExposure to semenEffect of semenNon-human primatesExpression of Mx1Anti-HIV mechanismsCervicovaginal mucosaSIVmac251 challengeSIVmac251 infectionCCR5 expressionIn vivo evidenceHIV acquisitionHIV infectionHIV transmissionAssociated with activationIncreased infiltrationRhesus macaquesReproductive tract
2010
Recovery of Multiple Ovulation Products via Uterine Flushing of Superovulated Rhesus Macaques.
Nichols S, Gierbolini L, Gonzalez-Martinez J, Bavister B. Recovery of Multiple Ovulation Products via Uterine Flushing of Superovulated Rhesus Macaques. Biology Of Reproduction 2010, 83: 680-680. DOI: 10.1093/biolreprod/83.s1.680.Peer-Reviewed Original ResearchRhesus monkeysUnfertilized oocytesUterine flushingsRhesus macaquesEmbryonic stem cell linesStem cell linesSite of ovulationEarly embryo developmentRates of embryo recoveryCervical cannulationResponse to exogenous hormonesRodent modelsStandard in vivoHormonal profileMultiplication in vivoAssisted reproductionEmbryo characteristicsCell linesNon-human primatesRhesusEmbryo developmentEmbryo recoveryHuman reproductive issuesBlastocystUterine