Correlates of Nontransmission in US Women at High Risk of Human Immunodeficiency Virus Type 1 Infection through Sexual Exposure
Skurnick JH, Palumbo P, DeVico A, Shacklett BL, Valentine FT, Merges M, Kamin-Lewis R, Mestecky J, Denny T, Lewis GK, Lloyd J, Praschunus R, Baker A, Nixon DF, Stranford S, Gallo R, Vermund SH, Louria DB. Correlates of Nontransmission in US Women at High Risk of Human Immunodeficiency Virus Type 1 Infection through Sexual Exposure. The Journal Of Infectious Diseases 2002, 185: 428-438. PMID: 11865394, PMCID: PMC2743095, DOI: 10.1086/338830.Peer-Reviewed Original ResearchConceptsSexual exposureSuppressive activityHuman immunodeficiency virus type 1 (HIV-1) infectionHigher CD8 cell countsHIV-1-suppressive activitySingle-cell cytokine productionHuman immunodeficiency virus type 1Macrophage inflammatory protein-1 betaVirus type 1 infectionHIV-positive male partnersInflammatory protein-1 betaMale partnersImmunodeficiency virus type 1CD4 cell responseCD8 cell countsHIV-positive donorsHIV-positive partnerHIV-negative partnersType 1 infectionInterferon-gamma secretionHIV-suppressive activityVirus type 1Apparent protective roleHIV antigenLocal antibodies