2024
Assessment of a screening tool to aid home-based identification of adolescents (aged 10–14) living with HIV in Zambia and South Africa: HPTN 071 (PopART) study
Chaila M, Mcleod D, Vermund S, Mbolongwe-Thornicroft M, Mbewe M, Mubekapi-Musadaidzwa C, Harper A, Schaap A, Floyd S, Hoddinott G, Hayes R, Fidler S, Ayles H, Shanaube K, Team O. Assessment of a screening tool to aid home-based identification of adolescents (aged 10–14) living with HIV in Zambia and South Africa: HPTN 071 (PopART) study. PLOS ONE 2024, 19: e0266573. PMID: 38363733, PMCID: PMC10871489, DOI: 10.1371/journal.pone.0266573.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildHIV InfectionsHumansMass ScreeningPredictive Value of TestsSouth AfricaZambiaConceptsScreening toolUniversal testingCommunity HIV-care providersCombination HIV prevention packageHIV-care providersHIV-positiveHIV prevention packageRapid HIV testingHIV test resultsRapid HIV test resultsHistory of hospital admissionIdentification of adolescentsPopART interventionUndiagnosed HIVHIV testingPrevention packageDoor-to-doorPoor healthHIV interventionsCommunity settingsConsented adolescentsHospital admissionSelf-reportSouth AfricaPopARTSpatiotemporal trends in COVID-19 vaccine sentiments on a social media platform and correlations with reported vaccine coverage
Zhou X, Zhang X, Larson H, de Figueiredo A, Jit M, Fodeh S, Vermund S, Zang S, Lin L, Hou Z. Spatiotemporal trends in COVID-19 vaccine sentiments on a social media platform and correlations with reported vaccine coverage. Bulletin Of The World Health Organization 2024, 102: 32-45. PMID: 38164328, PMCID: PMC10753281, DOI: 10.2471/blt.23.289682.Peer-Reviewed Original Research
2023
Increasing Spiritual Beliefs are Associated With Lower HIV Incidence Among Black Men Who Have Sex With Men: Results From HPTN 061 Longitudinal Study
Ransome Y, Taggart T, Huang A, Vermund S, Mayer K, Nunn A. Increasing Spiritual Beliefs are Associated With Lower HIV Incidence Among Black Men Who Have Sex With Men: Results From HPTN 061 Longitudinal Study. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2023, 94: 196-202. PMID: 37850978, DOI: 10.1097/qai.0000000000003278.Peer-Reviewed Original ResearchConceptsHIV seroconversionHIV incidenceBehavioral HIV prevention interventionsLower HIV incidenceProportional hazards regressionHIV prevention interventionsBlack menSpiritual beliefsOne-unit increaseHazards regressionLongitudinal riskPrevention interventionsHIVBiomedical assessmentLower hazard rateLongitudinal studyMenMonthsSeroconversionLongitudinal analysisReligious service attendanceIncidenceBaselineBMSMHigher proportionBrief Report: How Do We Reach Men? Offering HIV Testing in Evenings and Weekends in the HPTN 071 (PopART) Community-Based Trial in South Africa
Yang B, Sloot R, Floyd S, Awoniyi D, Griffith S, Ayles H, Fidler S, Hayes R, Vermund S, Bock P, team H. Brief Report: How Do We Reach Men? Offering HIV Testing in Evenings and Weekends in the HPTN 071 (PopART) Community-Based Trial in South Africa. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2023, 93: 300-304. PMID: 37001128, PMCID: PMC10313787, DOI: 10.1097/qai.0000000000003197.Peer-Reviewed Original ResearchConceptsHIV testingHousehold visitsWeekday shiftsNumber of menCommunity HIV care providersCommunity-based HIV testingHIV care providersHPTN 071 (PopART) trialUnknown HIV statusHigh-burden settingsAntiretroviral treatment coverageCommunity-based trialHigh-risk behaviorsCommunity-based servicesPopART interventionHIV statusHIV epidemicTreatment coverageCare providersLinear regression analysisStudy questionnaireMore menRecruitment of menVisitsWomen
2022
Voluntary Medical Male Circumcision for HIV Prevention: a Global Overview
Zhang C, Vermund S. Voluntary Medical Male Circumcision for HIV Prevention: a Global Overview. Current HIV/AIDS Reports 2022, 19: 474-483. PMID: 36348186, DOI: 10.1007/s11904-022-00632-y.Peer-Reviewed Original ResearchConceptsVoluntary medical male circumcisionMedical male circumcisionHIV preventionMale circumcisionPrevention strategiesEvidence-based HIV prevention strategiesBehavioral prevention strategiesHigher sexual risk behaviorsHIV prevention strategiesSexual risk behaviorsPurpose of ReviewWithDecreased riskClinical trialsCircumcision coverageVMMC coverageProtective effectRecent FindingsThereHealth professionalsSystematic reviewIncidence areaRisk behaviorsSexual partnersHealth authoritiesHealth systemMale partners
2021
Report From the National Academies of Sciences, Engineering and Medicine—STI: Adopting a Sexual Health Paradigm—A Synopsis for Sexually Transmitted Infection Practitioners, Clinicians, and Researchers
Rietmeijer CA, Kissinger PJ, Guilamo-Ramos V, Gaydos CA, Hook EW, Mead A, Yang S, Geller A, Vermund SH. Report From the National Academies of Sciences, Engineering and Medicine—STI: Adopting a Sexual Health Paradigm—A Synopsis for Sexually Transmitted Infection Practitioners, Clinicians, and Researchers. Sexually Transmitted Diseases 2021, 49: 169-175. PMID: 34475355, PMCID: PMC9365299, DOI: 10.1097/olq.0000000000001552.Peer-Reviewed Original ResearchConceptsSexual health paradigmMedicine reportFuture public health programsDisease intervention specialistsSexual health practitionersPublic health staffCommunity outreach workersPublic health advancesPublic health programsTransmitted InfectionsSTI managementHealth staffHidden epidemicHealth paradigmSexual healthHealth programsReportable STIsSexual debutHealth practitionersSTIsOutreach workersHealth advancesIntervention specialistsInfectionCliniciansWhere Should Orphaned and Separated Children and Adolescents Live: Comparing Institutionalized- and Family-Based Venues in Kenya
Vermund SH. Where Should Orphaned and Separated Children and Adolescents Live: Comparing Institutionalized- and Family-Based Venues in Kenya. JAMA Network Open 2021, 4: e2125572. PMID: 34529069, PMCID: PMC10773959, DOI: 10.1001/jamanetworkopen.2021.25572.Peer-Reviewed Original ResearchPoor retention and care-related sex disparities among youth living with HIV in rural Mozambique
Ahonkhai AA, Aliyu MH, Audet CM, Bravo M, Simmons M, Claquin G, Memiah P, Fernando AN, Carlucci JG, Shepherd BE, Van Rompaey S, Yu Z, Gong W, Vermund SH, Wester CW. Poor retention and care-related sex disparities among youth living with HIV in rural Mozambique. PLOS ONE 2021, 16: e0250921. PMID: 34019582, PMCID: PMC8139489, DOI: 10.1371/journal.pone.0250921.Peer-Reviewed Original ResearchConceptsHigher oddsCombination antiretroviral therapy (cART) initiationCox proportional hazards modelCare continuum outcomesComprehensive HIV programsPost-ART initiationYoung adults 15Antiretroviral therapy initiationRetrospective cohort studySex-related disparitiesMultivariable logistic regressionOne-year followProportional hazards modelYears of agePL femalesSex-related differencesART initiationAYA cohortTherapy initiationCohort studyContinuum outcomesHIV outcomesClinical visitsAdults 15HIV programsReopening Schools After a Novel Coronavirus Surge
Li D, Lin EZ, Brault MA, Paquette J, Vermund SH, Godri Pollitt KJ. Reopening Schools After a Novel Coronavirus Surge. Advances In Experimental Medicine And Biology 2021, 1318: 785-813. PMID: 33973212, DOI: 10.1007/978-3-030-63761-3_44.Peer-Reviewed Original ResearchConceptsCoronavirus disease 2019 (COVID-19) pandemicDisease 2019 pandemicGlobal death tollMental health supportPandemic influenzaDisease controlHealth supportSocial isolationNew guidelinesVulnerability of childrenRisk reductionRiskDisease control strategiesSafetyChild safetySpecial considerationDeath tollOpening schoolsPandemicFactors associated with past HIV testing among men who have sex with men attending university in China: a cross-sectional study*
Ye R, Liu C, Tan S, Li J, Simoni JM, Turner D, Nelson LE, Vermund SH, Wang N, Qian HZ. Factors associated with past HIV testing among men who have sex with men attending university in China: a cross-sectional study*. Sexual Health 2021, 18: 58-63. PMID: 33639685, PMCID: PMC10767712, DOI: 10.1071/sh20088.Peer-Reviewed Original ResearchConceptsPast HIV testingHIV testing ratesLog-binomial modelsHIV testingStudent MSMTesting ratesMultivariable log-binomial modelsBackground HIV prevalenceHIV testing experiencePositive HIV diagnosisIntervention clinical trialsLow HIV riskCross-sectional studySelf-reported barriersFirst sexual intercourseHIV diagnosisHIV testMedian ageHIV prevalenceClinical trialsHIV riskMSM participantsPositive diagnosisOlder ageBaseline survey
2019
Effect of Universal Testing and Treatment on HIV Incidence — HPTN 071 (PopART)
Hayes RJ, Donnell D, Floyd S, Mandla N, Bwalya J, Sabapathy K, Yang B, Phiri M, Schaap A, Eshleman SH, Piwowar-Manning E, Kosloff B, James A, Skalland T, Wilson E, Emel L, Macleod D, Dunbar R, Simwinga M, Makola N, Bond V, Hoddinott G, Moore A, Griffith S, Deshmane Sista N, Vermund SH, El-Sadr W, Burns DN, Hargreaves JR, Hauck K, Fraser C, Shanaube K, Bock P, Beyers N, Ayles H, Fidler S. Effect of Universal Testing and Treatment on HIV Incidence — HPTN 071 (PopART). New England Journal Of Medicine 2019, 381: 207-218. PMID: 31314965, PMCID: PMC6587177, DOI: 10.1056/nejmoa1814556.Peer-Reviewed Original ResearchConceptsHIV-positive participantsViral suppressionHIV infectionGroup BGroup AGroup CMonth 12Universal testingPrevention interventionsPopulation cohortHuman immunodeficiency virus (HIV) infectionHome-based HIV testingBaseline HIV prevalenceCombination prevention interventionsImmunodeficiency virus infectionHIV-positive adultsPopulation-level incidenceNew HIV infectionsAdjusted rate ratiosCommunity-randomized trialLack of effectHIV carePrevious trial resultsStandard careART adherenceModeling economic and epidemiological impact of voluntary medical male circumcision among men who have sex with men in Beijing, China
Zhang C, Penson DF, Qian HZ, Webb GF, Lou J, Shephard BE, Liu Y, Vermund SH. Modeling economic and epidemiological impact of voluntary medical male circumcision among men who have sex with men in Beijing, China. International Journal Of STD & AIDS 2019, 30: 630-638. PMID: 30890118, PMCID: PMC6666307, DOI: 10.1177/0956462419831859.Peer-Reviewed Original ResearchConceptsVoluntary medical male circumcisionNew HIV casesMedical male circumcisionHIV casesMale circumcisionHIV/AIDS epidemicCoverage rateHIV acquisitionHIV incidenceCumulative numberCircumcision ratesDeterministic compartmental modelEpidemiological impactVMMC implementationAIDS epidemicMenMSMCircumcisionSexYearsCompartmental modelCasesIncidence
2018
HIV-1 Transmission Clustering and Phylodynamics Highlight the Important Role of Young Men Who Have Sex with Men
Dennis AM, Volz E, Frost A, Hossain M, Poon AFY, Rebeiro P, Vermund SH, Sterling TR, Kalish ML. HIV-1 Transmission Clustering and Phylodynamics Highlight the Important Role of Young Men Who Have Sex with Men. AIDS Research And Human Retroviruses 2018, 34: 879-888. PMID: 30027754, PMCID: PMC6204570, DOI: 10.1089/aid.2018.0039.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsCluster AnalysisCross-Sectional StudiesFemaleGenotypeHIV InfectionsHIV-1Homosexuality, MaleHumansMaleMiddle AgedMolecular EpidemiologyPhylogenyPol Gene Products, Human Immunodeficiency VirusRetrospective StudiesRisk FactorsRNA, ViralSequence Analysis, DNATennesseeYoung AdultConceptsYoung MSMTransmission clustersHIV-1 pol sequencesTransmission riskComprehensive Care ClinicHIV transmission patternsVanderbilt Comprehensive Care ClinicYears of ageHIV molecular epidemiologyCross-sectional analysisHigh transmission riskClinical factorsCare clinicsRisk ratioClinical dataImportance of interventionsMSM riskPol sequencesTransmission clusteringYounger ageRisk behaviorsLogistic regressionMolecular epidemiologyMSMYoung menRisk Prediction Score for HIV Infection: Development and Internal Validation with Cross-Sectional Data from Men Who Have Sex with Men in China
Yin L, Zhao Y, Peratikos MB, Song L, Zhang X, Xin R, Sun Z, Xu Y, Zhang L, Hu Y, Hao C, Ruan Y, Shao Y, Vermund SH, Qian HZ. Risk Prediction Score for HIV Infection: Development and Internal Validation with Cross-Sectional Data from Men Who Have Sex with Men in China. AIDS And Behavior 2018, 22: 2267-2276. PMID: 29786768, PMCID: PMC7024582, DOI: 10.1007/s10461-018-2129-y.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAlcohol DrinkingChinaCondomsCross-Sectional StudiesHIV InfectionsHomosexuality, MaleHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisPrevalenceRisk AssessmentRisk FactorsRisk-TakingSafe SexSexual and Gender MinoritiesSexual BehaviorSexual PartnersSurveys and QuestionnairesSyphilisUnsafe SexYoung AdultConceptsHIV infectionRisk scoreHuman immunodeficiency virus (HIV) riskMultivariable logistic regression modelingBootstrap-corrected C-indexMultiple male sexual partnersValid risk scoreVaccine clinical trialsHigh-risk MSMHigh-risk personsRisk prediction scoreReceptive anal intercourseReceptive anal sexInconsistent condom useMale sexual partnersHIV prevention programmingLogistic regression modelingDrug/alcohol addictionHIV acquisitionRisk reduction programsSyphilis infectionHIV prevalenceClinical trialsC-indexIllegal drug useSubjective Well-being and Family Functioning among Adolescents Left Behind by Migrating Parents in Jiangxi Province, China
Zhou J, Hu F, Wu J, Zou ZY, Wang YX, Peng HC, Vermund SH, Hu YF, Ma YH. Subjective Well-being and Family Functioning among Adolescents Left Behind by Migrating Parents in Jiangxi Province, China. Biomedical And Environmental Sciences 2018, 31: 382-388. PMID: 29866220, PMCID: PMC9316390, DOI: 10.3967/bes2018.049.Peer-Reviewed Original ResearchConceptsLow academic performanceMental health challengesStructural equation modelMiddle school studentsAdolescent viewpointLife satisfactionAcademic performanceAdolescentsParental migrationSchool studentsParentsMigrant parentsEquation modelParticipantsSatisfactionBeingHealth challengesFamilyStudents
2017
Differences in health-related quality of life between HIV-positive and HIV-negative people in Zambia and South Africa: a cross-sectional baseline survey of the HPTN 071 (PopART) trial
Thomas R, Burger R, Harper A, Kanema S, Mwenge L, Vanqa N, Bell-Mandla N, Smith P, Floyd S, Bock P, Ayles H, Beyers N, Donnell D, Fidler S, Hayes R, Hauck K, Team H, Hargreaves J, Watson-Jones D, Godfrey-Faussett P, Cori A, Pickles M, Mandla N, Yang B, James A, Vermaak R, Makola N, Hoddinott G, Naidoo V, Bond V, Simwinga M, Mwinga A, Kosloff B, Limbada M, Bwalya J, Ngulube C, Fraser C, Eshleman S, Agyei Y, Cummings V, Catalano D, Emel L, Bunts L, Noble H, Burns D, Kouda A, Sista N, Moore A, White R, Headen T, Miller E, Hinson K, Vermund S, Barnes M, Horn L, Mwango A, Baldwin M, Wolf S, Hughes E. Differences in health-related quality of life between HIV-positive and HIV-negative people in Zambia and South Africa: a cross-sectional baseline survey of the HPTN 071 (PopART) trial. The Lancet Global Health 2017, 5: e1133-e1141. PMID: 28964756, PMCID: PMC5640509, DOI: 10.1016/s2214-109x(17)30367-4.Peer-Reviewed Original ResearchConceptsHIV-negative peopleHIV-positive individualsHIV-negative individualsAntiretroviral therapyHealth-related qualityHIV careHRQoL scoresHIV statusHerpes simplex virus type-2 statusNational InstituteHPTN 071 (PopART) studyHPTN 071 (PopART) trialLaboratory-confirmed HIVType 2 statusCross-sectional baseline surveyLarge cross-sectional surveyRecreational drug useCross-sectional surveyPresident's Emergency PlanGeneral population sampleHRQoL informationBetter HRQoLHIV-negativeHIV progressionHRQoL dataMonitoring Anesthesia Care Delivery and Perioperative Mortality in Kenya Utilizing a Provider-driven Novel Data Collection Tool
Sileshi B, Newton MW, Kiptanui J, Shotwell MS, Wanderer JP, Mungai M, Scherdin J, Harris PA, Vermund SH, Sandberg WS, McEvoy MD. Monitoring Anesthesia Care Delivery and Perioperative Mortality in Kenya Utilizing a Provider-driven Novel Data Collection Tool. Anesthesiology 2017, 127: 250-271. PMID: 28657959, PMCID: PMC5519082, DOI: 10.1097/aln.0000000000001713.Peer-Reviewed Original ResearchConceptsPerioperative dataPerioperative mortality rateTertiary referral hospitalMortality rate differencesAnesthesia care deliveryLogistic regression modelsMiddle-income settingsPerioperative mortalityCesarean deliveryEmergency surgeryMiddle-income countriesPerioperative careReferral hospitalSurgery typeSingle centerProcedure typeGeneral surgeryHigh riskMortality rateCare deliveryMortalityData collection periodData collection toolSurgeryRegression modelsHIV status disclosure, facility-based delivery and postpartum retention of mothers in a prevention clinical trial in rural Nigeria
Sarko KA, Blevins M, Ahonkhai AA, Audet CM, Moon TD, Gebi UI, Gana AM, Wester CW, Vermund SH, Aliyu MH. HIV status disclosure, facility-based delivery and postpartum retention of mothers in a prevention clinical trial in rural Nigeria. International Health 2017, 9: 243-251. PMID: 28810669, PMCID: PMC5881261, DOI: 10.1093/inthealth/ihx023.Peer-Reviewed Original ResearchConceptsHIV status disclosureFacility-based deliveryPostpartum retentionStatus disclosureHIV statusIntervention armWeeks postpartumChild HIV transmission (PMTCT) trialTrial intervention armPrevention of motherUnknown HIV statusPrevention clinical trialsMixed-effects logistic regressionEffects logistic regressionPMTCT continuumHIV careTreatment-naïveAntenatal carePregnant womenFacility deliveryMaternal ageObstetric servicesCare measuresClinical trialsHealth facilitiesAdolescents, young people, and the 90–90–90 goals
Wong VJ, Murray KR, Phelps BR, Vermund SH, McCarraher DR. Adolescents, young people, and the 90–90–90 goals. AIDS 2017, 31: s191-s194. PMID: 28665876, PMCID: PMC5497776, DOI: 10.1097/qad.0000000000001539.Peer-Reviewed Original ResearchConceptsHIV testingTreatment initiationJoint United Nations ProgrammeYoung people ages 15People ages 15AIDS 90HIV diagnosisUnited Nations ProgrammePrimary preventionEarly diagnosisHIVNew infectionsAge 15Nations ProgrammeDiagnosisEpidemic controlAdolescentsProgram plannersCurrent low ratesLower ratesYoung peopleNumber of youthRecent studiesTreatmentInitiationThe case for integrated human papillomavirus vaccine and HIV prevention with broader sexual and reproductive health and rights services for adolescent girls and young women
Narasimhan M, Pedersen H, Ogilvie G, Vermund SH. The case for integrated human papillomavirus vaccine and HIV prevention with broader sexual and reproductive health and rights services for adolescent girls and young women. Transactions Of The Royal Society Of Tropical Medicine And Hygiene 2017, 111: 141-143. PMID: 28673020, PMCID: PMC6257065, DOI: 10.1093/trstmh/trx032.Peer-Reviewed Original Research