2000
T-Lymphocyte Subsets in HIV-Infected and High-Risk HIV-Uninfected Adolescents: Retention of Naive T Lymphocytes in HIV-Infected Adolescents
Douglas SD, Rudy B, Muenz L, Starr SE, Campbell DE, Wilson C, Holland C, Crowley-Nowick P, Vermund SH. T-Lymphocyte Subsets in HIV-Infected and High-Risk HIV-Uninfected Adolescents: Retention of Naive T Lymphocytes in HIV-Infected Adolescents. JAMA Pediatrics 2000, 154: 375-380. PMID: 10768676, DOI: 10.1001/archpedi.154.4.375.Peer-Reviewed Original ResearchConceptsHIV-negative youthHuman immunodeficiency virus-infected adolescentsT lymphocyte subsetsNaive CD8Total CD4Immune systemCell countHIV infectionAdolescent careAdolescent Medicine HIV/AIDS Research NetworkHuman immunodeficiency virus (HIV) infectionHealth ProjectActive antiretroviral therapyCohort of HIVPercentage of CD4HIV-negative controlsHIV-positive subjectsImmunodeficiency virus infectionAIDS Research NetworkHigh-risk HIVT lymphocyte responsesHIV-negative adolescentsNaive T lymphocytesMemory cell populationsSignificant increase
1999
Peripheral blood mononuclear cell markers in antiretroviral therapy-naive HIV-infected and high risk seronegative adolescents
Douglas S, Rudy B, Muenz L, Moscicki A, Wilson C, Holland C, Crowley-Nowick P, Vermund S. Peripheral blood mononuclear cell markers in antiretroviral therapy-naive HIV-infected and high risk seronegative adolescents. AIDS 1999, 13: 1629-1635. PMID: 10509563, DOI: 10.1097/00002030-199909100-00005.Peer-Reviewed Original ResearchConceptsAdolescent Medicine HIV/AIDS Research NetworkHIV-negative adolescentsHIV-negative femalesHIV-positive femalesHIV-positive adolescentsAntiretroviral therapyHIV infectionHealthy adolescentsAntiretroviral therapy-naive HIVTotal CD4 cell countsThree-color flow cytometryMononuclear cell markersNaive CD8 cellsTherapy-naive HIVCD4 cell countHIV-negative subjectsHIV-positive malesAIDS Research NetworkHigh-risk HIVCD8 memory cellsNatural killer cellsTotal leukocyte countREACH cohortSeronegative adolescentsCD8 cells