2023
Brief Report: How Do We Reach Men? Offering HIV Testing in Evenings and Weekends in the HPTN 071 (PopART) Community-Based Trial in South Africa
Yang B, Sloot R, Floyd S, Awoniyi D, Griffith S, Ayles H, Fidler S, Hayes R, Vermund S, Bock P, team H. Brief Report: How Do We Reach Men? Offering HIV Testing in Evenings and Weekends in the HPTN 071 (PopART) Community-Based Trial in South Africa. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2023, 93: 300-304. PMID: 37001128, PMCID: PMC10313787, DOI: 10.1097/qai.0000000000003197.Peer-Reviewed Original ResearchConceptsHIV testingHousehold visitsWeekday shiftsNumber of menCommunity HIV care providersCommunity-based HIV testingHIV care providersHPTN 071 (PopART) trialUnknown HIV statusHigh-burden settingsAntiretroviral treatment coverageCommunity-based trialHigh-risk behaviorsCommunity-based servicesPopART interventionHIV statusHIV epidemicTreatment coverageCare providersLinear regression analysisStudy questionnaireMore menRecruitment of menVisitsWomenHigh-Level Drug-Resistant Mutations among HIV-1 Subtype A6 and CRF02_AG in Kazakhstan
Sanaubarova A, Pujol-Hodge E, Dzissyuk N, Lemey P, Vermund S, Brown A, Ali S. High-Level Drug-Resistant Mutations among HIV-1 Subtype A6 and CRF02_AG in Kazakhstan. Viruses 2023, 15: 1407. PMID: 37515095, PMCID: PMC10384832, DOI: 10.3390/v15071407.Peer-Reviewed Original ResearchConceptsAntiretroviral therapySubtype A6Drug-resistant mutationsDrug resistanceEffective antiretroviral therapySuppressive antiretroviral therapyAntiretroviral drug resistanceDrug resistance monitoringHigh-level drug resistanceDrug regimensHIV incidenceHIV epidemicHIV-1Sustained transmissionMolecular epidemiologySubtypesPLHIVHIVG190SDifferent mutational pathwaysMutationsK101ED67NHigh levelsA62V
2022
Projected outcomes of universal testing and treatment in a generalised HIV epidemic in Zambia and South Africa (the HPTN 071 [PopART] trial): a modelling study
Probert W, Sauter R, Pickles M, Cori A, Bell-Mandla N, Bwalya J, Abeler-Dörner L, Bock P, Donnell D, Floyd S, Macleod D, Piwowar-Manning E, Skalland T, Shanaube K, Wilson E, Yang B, Ayles H, Fidler S, Hayes R, Fraser C, Team H, Hayes R, Fidler S, Beyers N, Ayles H, Bock P, El-Sadr W, Cohen M, Eshleman S, Agyei Y, Piwowar-Manning E, Bond V, Hoddinott G, Donnell D, Floyd S, Wilson E, Emel L, Noble H, Macleod D, Burns D, Fraser C, Cori A, Sista N, Griffith S, Moore A, Headen T, White R, Miller E, Hargreaves J, Hauck K, Thomas R, Limbada M, Bwalya J, Pickles M, Sabapathy K, Schaap, Dunbar R, Shanaube K, Yang B, Simwinga M, Smith P, Vermund S, Mandla N, Makola N, van Deventer A, James A, Jennings K, Kruger J, Phiri M, Kosloff B, Mwenge L, Kanema S, Sauter R, Probert W, Kumar R, Sakala E, Silumesi A, Skalland T, Yuhas K. Projected outcomes of universal testing and treatment in a generalised HIV epidemic in Zambia and South Africa (the HPTN 071 [PopART] trial): a modelling study. The Lancet HIV 2022, 9: e771-e780. PMID: 36332654, PMCID: PMC9646978, DOI: 10.1016/s2352-3018(22)00259-4.Peer-Reviewed Original ResearchConceptsStandard of careHome-based testingCluster-randomised trialHigh-prevalence communitiesHIV incidenceHIV epidemicNational guidelinesNational InstituteUniversal testingHIV care cascadeAntiretroviral therapy uptakeUS President's Emergency PlanGeneralised HIV epidemicPresident's Emergency PlanPopART interventionCare cascadeART eligibilityArm BTherapy uptakeTrial interventionTrial dataInfectious diseasesAIDS ReliefIntervention impactDrug abuse
2019
Interventions to improve the HIV continuum of care in China
Zhang X, Wang N, Vermund SH, Zou H, Li X, Zhang F, Qian HZ. Interventions to improve the HIV continuum of care in China. Current HIV/AIDS Reports 2019, 16: 448-457. PMID: 31776975, PMCID: PMC10767704, DOI: 10.1007/s11904-019-00469-y.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyHIV continuumHIV epidemicPublic health intervention programsFree ART programHIV sexual transmissionHIV testing campaignsFormer plasma donorsPurpose of ReviewToHealth intervention programsTwo-thirdsViral suppressionHeterosexual transmissionPediatric mortalitySexual transmissionRisk groupsMore infectionsPlasma donorsRecent FindingsTheIntervention programsYoung menCareHIVHeterosexual menLower ratesVoluntary medical male circumcision and HIV infection among men who have sex with men: Implications from a systematic review
Zhang C, Qian HZ, Liu Y, Vermund SH. Voluntary medical male circumcision and HIV infection among men who have sex with men: Implications from a systematic review. SAGE Open Medicine 2019, 7: 2050312119869110. PMID: 31448119, PMCID: PMC6689924, DOI: 10.1177/2050312119869110.Peer-Reviewed Original ResearchVoluntary medical male circumcisionMedical male circumcisionMale circumcisionSystematic reviewHIV infectionProtective effectPotential protective effectArticles/abstractsMeta-Analyses (PRISMA) guidelinesRandomized control trialPreferred Reporting ItemsRandom-effects modelKey study characteristicsComprehensive literature searchSubgroup analysisHIV epidemicHIV preventionHIV riskControl trialReporting ItemsStudy characteristicsLiterature searchCircumcisionSexMen
2017
Adapting an adherence support workers intervention: engaging traditional healers as adherence partners for persons enrolled in HIV care and treatment in rural Mozambique
Audet CM, Salato J, Vermund SH, Amico KR. Adapting an adherence support workers intervention: engaging traditional healers as adherence partners for persons enrolled in HIV care and treatment in rural Mozambique. Implementation Science 2017, 12: 50. PMID: 28407813, PMCID: PMC5390357, DOI: 10.1186/s13012-017-0582-z.Peer-Reviewed Original ResearchConceptsCommunity health workersAntiretroviral therapyWorker interventionTraditional healersHealth workersHealth systemAllopathic health systemEvidence-informed interventionsLow-literacy populationsHIV careHIV diagnosisRural MozambiquePatient adherenceHIV epidemicHealth facilitiesClinical careHealthcare providersHealth workforceHIVTraditional treatmentCommunity-based activitiesInterventionTraditional medicineCareSuccessful program implementation
2016
Sexual Behaviors Linked to Drug and Alcohol Use Among Men Who Have Sex With Men in China
Zhang C, Qian HZ, Yin L, Liu Y, Strauss SM, Ruan Y, Shao Y, Lu H, Vermund SH. Sexual Behaviors Linked to Drug and Alcohol Use Among Men Who Have Sex With Men in China. Substance Use & Misuse 2016, 51: 1821-1830. PMID: 27608264, PMCID: PMC5423713, DOI: 10.1080/10826084.2016.1197264.Peer-Reviewed Original ResearchConceptsAlcohol useHigher oddsAlcohol consumptionSexual behaviorDrug useHigh-risk sexual behaviorFemale partnersHistory of alcoholSexual risk behaviorsHigh-risk behaviorsEffects of drugsSelf-administered questionnaireSyphilis infectionHIV infectionSyphilis prevalenceMean ageSyphilis testingClinical trialsHIV epidemicHIV interventionsBlood samplesHIVHan ethnicityRisk behaviorsMSMFrequent HIV Testing
Liu Y, Qian HZ, Ruan Y, Wu P, Osborn CY, Jia Y, Yin L, Lu H, He X, Shao Y, Vermund SH. Frequent HIV Testing. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2016, 72: 452-461. PMID: 27003496, PMCID: PMC4925192, DOI: 10.1097/qai.0000000000001001.Peer-Reviewed Original ResearchConceptsMultivariable logistic regression analysisCurrent HIV infectionHIV incidence reductionHIV testing historyPropensity score adjustmentCubic spline modelingBorderline significant trendLogistic regression analysisHigher testing ratesHIV infectionHIV serostatusPrevious HIVHIV epidemicBeijing MSMTesting ratesScore adjustmentIncidence reductionTesting historyHIVInfection statusBehavioral factorsRegression analysisMSMOddsMenSeeking Male Sexual Partners via Internet and Traditional Venues among Chinese Men Who Have Sex with Men: Implications for HIV Risk Reduction Interventions
Liu Y, Wang J, Qian HZ, Liu H, Yin L, Lu H, Zhang C, Ruan Y, Shao Y, Vermund SH. Seeking Male Sexual Partners via Internet and Traditional Venues among Chinese Men Who Have Sex with Men: Implications for HIV Risk Reduction Interventions. AIDS And Behavior 2016, 20: 2222-2230. PMID: 27000143, PMCID: PMC7784627, DOI: 10.1007/s10461-016-1371-4.Peer-Reviewed Original ResearchConceptsMale sexual partnersChinese menSexual partnersHIV risk reduction interventionsCondomless receptive anal sexReceptive anal sexRisk reduction interventionsBehaviors of MSMCross-sectional surveyHigh-risk behaviorsHIV epidemicChinese MSMAnal sexReduction interventionsMSMSociodemographic predictorsLonger durationSexMenInterventionHigher incomeHIVTraditional venues
2014
Global HIV Epidemiology: A Guide for Strategies in Prevention and Care
Vermund SH. Global HIV Epidemiology: A Guide for Strategies in Prevention and Care. Current HIV/AIDS Reports 2014, 11: 93-98. PMID: 24691698, PMCID: PMC4042676, DOI: 10.1007/s11904-014-0208-x.Peer-Reviewed Original ResearchConceptsRisk populationsFemale sex worker cohortSex worker cohortPrevention of motherOpiate substitution therapyHIV prevention strategiesConsiderable clinical benefitPublic health approachRepresentative population sampleLow infectiousnessAntiretroviral therapyChild transmissionHIV incidenceClinical benefitSubstitution therapyConcentrated epidemicsHIV epidemicSentinel populationYoung MSMPrevalence surveyGeneralized epidemicsIncidence estimatesNeedle useEffective carePrevention servicesModeling the Impact on HIV Incidence of Combination Prevention Strategies among Men Who Have Sex with Men in Beijing, China
Lou J, Blevins M, Ruan Y, Vermund SH, Tang S, Webb GF, Shepherd BE, He X, Lu H, Shao Y, Qian HZ. Modeling the Impact on HIV Incidence of Combination Prevention Strategies among Men Who Have Sex with Men in Beijing, China. PLOS ONE 2014, 9: e90985. PMID: 24626165, PMCID: PMC3953201, DOI: 10.1371/journal.pone.0090985.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyHIV epidemicCondom useHIV prevalenceART coverageCombination prevention strategiesHIV/AIDSHIV testingHIV incidenceCombination interventionsBeijing MSMPrevention strategiesPrevalence estimatesPrevalenceEpidemic expansionMenInterventionEpidemicIncidenceBasic reproduction numberPrevention scenariosCurrent coverageSexReproduction numberIntervention levels
2012
Effectiveness of Integrated HIV Prevention Interventions among Chinese Men Who Have Sex with Men: Evaluation of a 16-City Public Health Program
Ye S, Xiao Y, Jin C, Cassell H, Blevins M, Sun J, Vermund SH, Qian HZ. Effectiveness of Integrated HIV Prevention Interventions among Chinese Men Who Have Sex with Men: Evaluation of a 16-City Public Health Program. PLOS ONE 2012, 7: e50873. PMID: 23300528, PMCID: PMC3534092, DOI: 10.1371/journal.pone.0050873.Peer-Reviewed Original ResearchConceptsPublic health programsSelf-reported receiptHIV prevalenceCondom useHealth programsLast sexMultivariable logistic regression analysisMale partnersLow HIV prevalenceHIV prevention interventionsLogistic regression analysisYearly cross-sectional surveysSelf-reported condom useCross-sectional surveyHIV infectionIndependent predictorsHIV epidemicMSM populationPrevention interventionsChinese menDisease ratesEffective interventionsPrevalenceInterventionSexHIV Epidemic
Vermund S. HIV Epidemic. Emerging Infectious Diseases Of The 21st Century 2012, 3-46. DOI: 10.1007/978-1-4614-4496-1_1.Peer-Reviewed Original ResearchHuman immunodeficiency virus (HIV) infectionImmunodeficiency virus infectionEra of antibioticsGlobal pandemicHIV epidemicVirus infectionSusceptible humansEpidemic formHIVDevastating diseaseInfectionEpidemicSuccessful controlImproved sanitationPlague bacteriumBubonic plagueYersinia pestisPandemicLess intensityRodent controlDiseaseThe HIV Epidemic: High-Income Countries
Vermund SH, Leigh-Brown AJ. The HIV Epidemic: High-Income Countries. Cold Spring Harbor Perspectives In Medicine 2012, 2: a007195. PMID: 22553497, PMCID: PMC3331688, DOI: 10.1101/cshperspect.a007195.Peer-Reviewed Original ResearchConceptsInjection drug useHIV epidemicDrug useNeedle/syringe sharingReceptive anal intercourseDifferent risk groupsRecent explosive epidemicsAntiretroviral therapyChild transmissionSyringe sharingAffected subgroupRisk groupsAnal intercourseVaginal intercourseHIV vulnerabilityExplosive epidemicsDiagnostic screeningEpidemicIncome countriesIntercourseUnited StatesSpecific strainsHigh-income nationsHIVTherapy
2010
Sociocultural and epidemiological aspects of HIV/AIDS in Mozambique
Audet CM, Burlison J, Moon TD, Sidat M, Vergara AE, Vermund SH. Sociocultural and epidemiological aspects of HIV/AIDS in Mozambique. BMC Public Health 2010, 10: 15. PMID: 20529358, PMCID: PMC2891693, DOI: 10.1186/1472-698x-10-15.Peer-Reviewed Original ResearchHIV/AIDSHealth care infrastructureHIV incidenceHIV epidemicSevere health worker shortagesHuman immunodeficiency virus (HIV) epidemicAntenatal clinic sitesChronic disease servicesAIDS mortality ratesHealth system strengtheningHealth worker shortagesHealth care systemTerms HIVDrug adherenceImmunodeficiency syndromeMost HIVHeterosexual infectionHIV prevalenceDisease servicesClinic sitesEpidemiological aspectsGeneral populationMortality ratePrevalence estimatesHIVEstimation of HIV-1 incidence among five focal populations in Dehong, Yunnan: a hard hit area along a major drug trafficking route
Duan S, Shen S, Bulterys M, Jia Y, Yang Y, Xiang L, Tian F, Lu L, Xiao Y, Wang M, Jia M, Jiang H, Vermund SH, Jiang Y. Estimation of HIV-1 incidence among five focal populations in Dehong, Yunnan: a hard hit area along a major drug trafficking route. BMC Public Health 2010, 10: 180. PMID: 20374618, PMCID: PMC2858119, DOI: 10.1186/1471-2458-10-180.Peer-Reviewed Original ResearchConceptsHIV incidenceDiscordant couplesHIV epidemicMajor drug trafficking routesRecent HIV-1 infectionAnnual HIV incidenceHIV-discordant couplesHIV-1 prevalenceHIV-1 incidenceHIV-1 infectionMigration of HIVFemale sex workersPre-marital couplesCross-sectional surveyBED IgGRecent seroconversionIntensive prevention measuresHIV-positivePregnant womenHIV preventionHigh riskResultsFrom 2004Drug usersMultivariate analysisEnzyme immunoassay
2008
Expansion of HIV and syphilis into the Peruvian Amazon: a survey of four communities of an indigenous Amazonian ethnic group
Bartlett EC, Zavaleta C, Fernández C, Razuri H, Vilcarromero S, Vermund SH, Gotuzzo E. Expansion of HIV and syphilis into the Peruvian Amazon: a survey of four communities of an indigenous Amazonian ethnic group. International Journal Of Infectious Diseases 2008, 12: e89-e94. PMID: 18760648, PMCID: PMC2610365, DOI: 10.1016/j.ijid.2008.03.036.Peer-Reviewed Original ResearchConceptsRisk factorsPrevalence ratesSyphilis prevalence ratesUrgent public health responsePrevalence of HIVCases of HIVExpansion of HIVHIV prevalence ratesPublic health responseHIV/AIDSHIV infectionHIV epidemicBlood samplesSyphilis transmissionHIVKnowledge/beliefsEthnic groupsHealth responseSyphilisRemote Amazonian communityPoor knowledgeInfectionConfirmatory testDemographic informationMSM activityPredictors of unprotected sex among men who have sex with men in Beijing, China.
Li X, Shi W, Li D, Ruan Y, Jia Y, Vermund SH, Zhang X, Wang C, Liu Y, Yu M, Xing H, Hong K, Shao Y. Predictors of unprotected sex among men who have sex with men in Beijing, China. The Southeast Asian Journal Of Tropical Medicine And Public Health 2008, 39: 99-108. PMID: 18567448, PMCID: PMC2730761.Peer-Reviewed Original ResearchConceptsUnprotected anal intercourseMale sex partnersSex partnersAnal intercourseMore male sex partnersMale partnersPrevalence of HIVReceptive anal intercourseCasual male partnersRegular male partnersCommunity-based surveyLow monthly incomeCasual sex partnersMale sex workersSyphilis infectionCondom promotionHIV epidemicUnprotected sexHIVSex workersPeer referralMenSexMonthly incomeInfection
2007
Sources of data for improved surveillance of HIV/AIDS in China.
Jia Y, Lu F, Sun X, Vermund SH. Sources of data for improved surveillance of HIV/AIDS in China. The Southeast Asian Journal Of Tropical Medicine And Public Health 2007, 38: 1041-52. PMID: 18613545, PMCID: PMC2730767.Peer-Reviewed Original ResearchConceptsHIV/AIDSHIV/AIDS surveillanceInjection drug usersImproved surveillanceAIDS surveillanceHuman immunodeficiency virus/HIV sentinel surveillanceImmunodeficiency syndrome surveillancePassive surveillanceEffective HIV prevention programsHIV prevention programsHIV/AIDS epidemicSurveillance systemHIV infectionSentinel surveillanceActive surveillanceHIV epidemicVirus/Syndrome surveillanceDrug usersPrevention programsAIDSAIDS epidemicComprehensive surveillanceSurveillance
2006
Expansion of HIV/AIDS in China: Lessons from Yunnan Province
Xiao Y, Kristensen S, Sun J, Lu L, Vermund SH. Expansion of HIV/AIDS in China: Lessons from Yunnan Province. Social Science & Medicine 2006, 64: 665-675. PMID: 17107739, PMCID: PMC2730760, DOI: 10.1016/j.socscimed.2006.09.019.Peer-Reviewed Original ResearchConceptsHIV control programsRisk behaviorsCommercial sex workGeneral populationHuman immunodeficiency virusEnglish-language literatureSexual contact ratesHIV/AIDSAntenatal careHIV infectionHIV subtypesImmunodeficiency virusSexual transmissionCondom promotionHIV outbreakHIV epidemicFuture HIVHIV awarenessDrug usersDrug useSex workInfection rateDisease controlDrug ratesLanguage literature