Cyst growth, polycystins, and primary cilia in autosomal dominant polycystic kidney disease
Lee SH, Somlo S. Cyst growth, polycystins, and primary cilia in autosomal dominant polycystic kidney disease. Kidney Research And Clinical Practice 2014, 33: 73-78. PMID: 26877954, PMCID: PMC4714135, DOI: 10.1016/j.krcp.2014.05.002.Peer-Reviewed Original ResearchPrimary ciliaAutosomal dominant polycystic kidney diseaseCarboxy-terminal tailDominant polycystic kidney diseaseExtracellular stimuliPolycystic kidney diseasePolycystin functionChannel proteinsPolycystinsPKD1 geneCystic kidney diseaseCiliaCalcium signalsRenal epitheliumProteinIntact ciliaKidney diseaseGenesCyst growthCurrent understandingReduced levelsPathwayComplete inactivationInactivationRecent data