Coexpressed EphA Receptors and Ephrin-A Ligands Mediate Opposing Actions on Growth Cone Navigation from Distinct Membrane Domains
Marquardt T, Shirasaki R, Ghosh S, Andrews SE, Carter N, Hunter T, Pfaff SL. Coexpressed EphA Receptors and Ephrin-A Ligands Mediate Opposing Actions on Growth Cone Navigation from Distinct Membrane Domains. Cell 2005, 121: 127-139. PMID: 15820684, DOI: 10.1016/j.cell.2005.01.020.Peer-Reviewed Original ResearchConceptsDistinct membrane domainsMembrane domainsGrowth conesContact-dependent signalingEph receptor tyrosine kinasesReceptor tyrosine kinasesNeuronal growth conesGrowth cone navigationEphA receptorsMotor neuron growth conesSubcellular arrangementGuidance receptorsNeuron growth conesTyrosine kinaseEphrin proteinsReceptor proteinCell typesEphrinProteinPathological processes