Instructive role of aPKCζ subcellular localization in the assembly of adherens junctions in neural progenitors
Ghosh S, Marquardt T, Thaler JP, Carter N, Andrews SE, Pfaff SL, Hunter T. Instructive role of aPKCζ subcellular localization in the assembly of adherens junctions in neural progenitors. Proceedings Of The National Academy Of Sciences Of The United States Of America 2008, 105: 335-340. PMID: 18162555, PMCID: PMC2224213, DOI: 10.1073/pnas.0705713105.Peer-Reviewed Original ResearchConceptsAdherens junctionsNeural progenitorsNeural tubeApical-basal polarityCell fate determinantsNeuronal precursorsApical adherens junctionsApical membranePKCzeta/lambdaCell-cell adhesionChicken neural tubeStem cell proliferationPostmitotic neuronal precursorsAsymmetric inheritanceApical assemblyFate determinantsAsymmetric localizationNeural stem cell proliferationSubcellular compartmentalizationSubcellular localizationNeural stem cellsKinase activityInstructive signalsNeurogenic divisionsInstructive role