2005
Testicular Immune Privilege Promotes Transplantation Tolerance by Altering the Balance between Memory and Regulatory T Cells
Nasr IW, Wang Y, Gao G, Deng S, Diggs L, Rothstein DM, Tellides G, Lakkis FG, Dai Z. Testicular Immune Privilege Promotes Transplantation Tolerance by Altering the Balance between Memory and Regulatory T Cells. The Journal Of Immunology 2005, 174: 6161-6168. PMID: 15879112, DOI: 10.4049/jimmunol.174.10.6161.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, BlockingApoptosisCD40 AntigensCD40 LigandCD8-Positive T-LymphocytesEpitopes, T-LymphocyteGraft RejectionGrowth InhibitorsImmunologic MemoryIslets of Langerhans TransplantationLymphocyte ActivationLymphocyte CountMaleMiceMice, Inbred BALB CMice, Inbred C3HMice, Inbred C57BLMice, KnockoutMice, TransgenicReceptors, Interleukin-2TestisT-Lymphocytes, RegulatoryTransplantation ToleranceTransplantation, HeterotopicConceptsRegulatory T cellsNon-privileged sitesIslet allograftsTransplantation toleranceT cellsImmune privilegeCD40/CD40L costimulationIntratesticular islet allograftsIslet allograft toleranceAcute allograft rejectionProlong allograft survivalLate allograft failureTesticular immune privilegePrivileged siteAllograft failureAllograft survivalAllograft toleranceCostimulatory blockadeAllograft rejectionAlloimmune responseSkin allograftsIslet transplantationImmune regulationImmune responseAllografts
2003
Cutting Edge: Transplantation Tolerance through Enhanced CTLA-4 Expression
Ariyan C, Salvalaggio P, Fecteau S, Deng S, Rogozinski L, Mandelbrot D, Sharpe A, Sayegh MH, Basadonna GP, Rothstein DM. Cutting Edge: Transplantation Tolerance through Enhanced CTLA-4 Expression. The Journal Of Immunology 2003, 171: 5673-5677. PMID: 14634073, DOI: 10.4049/jimmunol.171.11.5673.Peer-Reviewed Original ResearchMeSH KeywordsAbataceptAdjuvants, ImmunologicAnimalsAntibodies, MonoclonalAntigens, CDAntigens, DifferentiationCTLA-4 AntigenGraft Enhancement, ImmunologicGraft SurvivalImmunoconjugatesInjections, IntraperitonealInjections, IntravenousIslets of Langerhans TransplantationLeukocyte Common AntigensMaleMiceMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutSignal TransductionTransplantation ToleranceUp-RegulationConceptsCTLA-4 expressionCTLA-4Allograft survivalCTLA4-IgAnti-CD45RB therapyIslet allograft survivalCTLA-4 interactionWild-type miceLong-term engraftmentPeripheral toleranceTransplantation toleranceAllogeneic cellsB7-1B7-2Requisite roleEngraftmentMiceB7SurvivalSpecific roleCritical roleExpressionTransplantationTherapyRecipients