2023
Trajectory of Gonadal Hormones in Adolescent Males up to 2 Years After Sleeve Gastrectomy
Kaur S, Bredella M, Misra M, Singhal V. Trajectory of Gonadal Hormones in Adolescent Males up to 2 Years After Sleeve Gastrectomy. Obesity Surgery 2023, 33: 3323-3326. PMID: 37561269, DOI: 10.1007/s11695-023-06759-0.Peer-Reviewed Original ResearchConceptsSertoli cell functionAssociated with degree of weight lossDegree of weight lossLeydig cell functionSleeve gastrectomyCell functionEffects of SGAssociated with degreeLong-term follow-up studiesWeight lossMale fertilitySertoliFollow-up studyNonsurgical controlsSG groupYoung adult malesTestosterone levelsGonadal hormonesMetabolic benefitsLeydigGastrectomyAdult malesAdolescentsTestisPreliminary studyMale Runners With Lower Energy Availability Have Impaired Skeletal Integrity Compared to Nonathletes
Haines M, Kaur S, Scarff G, Lauze M, Gerweck A, Slattery M, Oreskovic N, Ackerman K, Tenforde A, Popp K, Bouxsein M, Miller K, Misra M. Male Runners With Lower Energy Availability Have Impaired Skeletal Integrity Compared to Nonathletes. The Journal Of Clinical Endocrinology & Metabolism 2023, 108: e1063-e1073. PMID: 37079740, PMCID: PMC10505543, DOI: 10.1210/clinem/dgad215.Peer-Reviewed Original ResearchConceptsBone mineral densityImpaired skeletal integrityMale runnersLean massCalcium intakeCaloric intakeRunning mileageSkeletal integrityBone mineral density Z-scoreLumbar spine BMD Z-scoreBSI riskTrabecular volumetric bone mineral densityImpaired bone mineral densitySpine BMD Z-scoreZ-scoreVolumetric bone mineral densityTibial failure loadBMD Z-scoresExercise energy expenditureInsufficient caloric intakeAppendicular lean massWeight-bearing activitiesBody mass indexTrabecular bone volume fractionEnergy expenditure
2022
Changes in Sex Steroids and Enteric Peptides After Sleeve Gastrectomy in Youth in Relation to Changes in Bone Parameters
Nimmala S, Kaur S, Singhal V, Mitchell D, Stanford F, Bouxsein M, Lauze M, Huynh C, Pedreira C, Lee H, Bredella M, Misra M. Changes in Sex Steroids and Enteric Peptides After Sleeve Gastrectomy in Youth in Relation to Changes in Bone Parameters. The Journal Of Clinical Endocrinology & Metabolism 2022, 107: e3747-e3758. PMID: 35689793, PMCID: PMC9387701, DOI: 10.1210/clinem/dgac361.Peer-Reviewed Original ResearchConceptsBody mass indexFree androgen indexSleeve gastrectomyVolumetric BMDEnteric peptidesSex steroidsLean massModerate-to-severe obesityDual-energy X-ray absorptiometry measurementsMeasurements of areal bone mineral densityBody compositionAreal bone mineral densityZ-scoreAssociated with changesMeasures of volumetric BMDImpaired bone healthBone turnover markersABMD Z-scoresFasting peptide YYBone mineral densityPeripheral quantitative computed tomographyResolution peripheral quantitative computed tomographyTertiary-care hospitalQuantitative computed tomographyMicrofinite element analysis