2023
Differences in bone accrual over one year in young girls with obesity compared to Normal weight controls
Singhal V, Kaur S, Haidar L, Lee H, Bredella M, Misra M. Differences in bone accrual over one year in young girls with obesity compared to Normal weight controls. Bone 2023, 172: 116757. PMID: 37030498, PMCID: PMC10198942, DOI: 10.1016/j.bone.2023.116757.Peer-Reviewed Original ResearchMeSH KeywordsAbsorptiometry, PhotonAdolescentAdultBone and BonesBone DensityFemaleFractures, BoneHumansObesityRadiusTibiaYoung AdultConceptsNormal-weight controlsBone mineral densityBone accrualVolumetric BMDBone healthTotal hip bone mineral densityPeak bone mass acquisitionDual-energy X-ray absorptiometryHip bone mineral densityIncreased risk of fractureAreal bone mineral densityModerate to severe obesityHigher bone mineral densityVolumetric bone mineral densityHigh-resolution peripheral quantitative computed tomographyNormal-weight womenBone mass acquisitionX-ray absorptiometryPeripheral quantitative computed tomographyYoung womenRisk of fractureResolution peripheral quantitative computed tomographyImpact of obesityYounger menarcheal ageQuantitative computed tomography
2022
Changes in Sex Steroids and Enteric Peptides After Sleeve Gastrectomy in Youth in Relation to Changes in Bone Parameters
Nimmala S, Kaur S, Singhal V, Mitchell D, Stanford F, Bouxsein M, Lauze M, Huynh C, Pedreira C, Lee H, Bredella M, Misra M. Changes in Sex Steroids and Enteric Peptides After Sleeve Gastrectomy in Youth in Relation to Changes in Bone Parameters. The Journal Of Clinical Endocrinology & Metabolism 2022, 107: e3747-e3758. PMID: 35689793, PMCID: PMC9387701, DOI: 10.1210/clinem/dgac361.Peer-Reviewed Original ResearchConceptsBody mass indexFree androgen indexSleeve gastrectomyVolumetric BMDEnteric peptidesSex steroidsLean massModerate-to-severe obesityDual-energy X-ray absorptiometry measurementsMeasurements of areal bone mineral densityBody compositionAreal bone mineral densityZ-scoreAssociated with changesMeasures of volumetric BMDImpaired bone healthBone turnover markersABMD Z-scoresFasting peptide YYBone mineral densityPeripheral quantitative computed tomographyResolution peripheral quantitative computed tomographyTertiary-care hospitalQuantitative computed tomographyMicrofinite element analysis