2023
Bone changes post-sleeve gastrectomy in relation to body mass and hormonal changes
Kaur S, Nimmala S, Singhal V, Mitchell D, Pedreira C, Lauze M, Lee H, Stanford F, Bouxsein M, Bredella M, Misra M. Bone changes post-sleeve gastrectomy in relation to body mass and hormonal changes. European Journal Of Endocrinology 2023, 189: 346-354. PMID: 37633255, PMCID: PMC11188938, DOI: 10.1093/ejendo/lvad121.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBody CompositionBone DensityEstroneFemaleGastrectomyHumansSpineYoung AdultConceptsSex hormone binding globulinTrabecular volumetric BMDABMD Z-scoresFree androgen indexNon-surgical controlsAreal bone mineral densityVolumetric BMDBMI z-scoreSleeve gastrectomyZ-scoreLean massModerate-to-severe obesityAssociated with bone lossAssociated with decreasesImpaired bone healthBone turnover markersBone mineral densityHigh-resolution peripheral quantitative CTPost sleeve gastrectomyMonths post-SGMicrofinite element analysisPeripheral quantitative CTSerum CTXTurnover markersPost-SGMale Runners With Lower Energy Availability Have Impaired Skeletal Integrity Compared to Nonathletes
Haines M, Kaur S, Scarff G, Lauze M, Gerweck A, Slattery M, Oreskovic N, Ackerman K, Tenforde A, Popp K, Bouxsein M, Miller K, Misra M. Male Runners With Lower Energy Availability Have Impaired Skeletal Integrity Compared to Nonathletes. The Journal Of Clinical Endocrinology & Metabolism 2023, 108: e1063-e1073. PMID: 37079740, PMCID: PMC10505543, DOI: 10.1210/clinem/dgad215.Peer-Reviewed Original ResearchConceptsBone mineral densityImpaired skeletal integrityMale runnersLean massCalcium intakeCaloric intakeRunning mileageSkeletal integrityBone mineral density Z-scoreLumbar spine BMD Z-scoreBSI riskTrabecular volumetric bone mineral densityImpaired bone mineral densitySpine BMD Z-scoreZ-scoreVolumetric bone mineral densityTibial failure loadBMD Z-scoresExercise energy expenditureInsufficient caloric intakeAppendicular lean massWeight-bearing activitiesBody mass indexTrabecular bone volume fractionEnergy expenditureDifferences in bone accrual over one year in young girls with obesity compared to Normal weight controls
Singhal V, Kaur S, Haidar L, Lee H, Bredella M, Misra M. Differences in bone accrual over one year in young girls with obesity compared to Normal weight controls. Bone 2023, 172: 116757. PMID: 37030498, PMCID: PMC10198942, DOI: 10.1016/j.bone.2023.116757.Peer-Reviewed Original ResearchConceptsNormal-weight controlsBone mineral densityBone accrualVolumetric BMDBone healthTotal hip bone mineral densityPeak bone mass acquisitionDual-energy X-ray absorptiometryHip bone mineral densityIncreased risk of fractureAreal bone mineral densityModerate to severe obesityHigher bone mineral densityVolumetric bone mineral densityHigh-resolution peripheral quantitative computed tomographyNormal-weight womenBone mass acquisitionX-ray absorptiometryPeripheral quantitative computed tomographyYoung womenRisk of fractureResolution peripheral quantitative computed tomographyImpact of obesityYounger menarcheal ageQuantitative computed tomography
2022
Changes in Sex Steroids and Enteric Peptides After Sleeve Gastrectomy in Youth in Relation to Changes in Bone Parameters
Nimmala S, Kaur S, Singhal V, Mitchell D, Stanford F, Bouxsein M, Lauze M, Huynh C, Pedreira C, Lee H, Bredella M, Misra M. Changes in Sex Steroids and Enteric Peptides After Sleeve Gastrectomy in Youth in Relation to Changes in Bone Parameters. The Journal Of Clinical Endocrinology & Metabolism 2022, 107: e3747-e3758. PMID: 35689793, PMCID: PMC9387701, DOI: 10.1210/clinem/dgac361.Peer-Reviewed Original ResearchConceptsBody mass indexFree androgen indexSleeve gastrectomyVolumetric BMDEnteric peptidesSex steroidsLean massModerate-to-severe obesityDual-energy X-ray absorptiometry measurementsMeasurements of areal bone mineral densityBody compositionAreal bone mineral densityZ-scoreAssociated with changesMeasures of volumetric BMDImpaired bone healthBone turnover markersABMD Z-scoresFasting peptide YYBone mineral densityPeripheral quantitative computed tomographyResolution peripheral quantitative computed tomographyTertiary-care hospitalQuantitative computed tomographyMicrofinite element analysis