2023
Bone changes post-sleeve gastrectomy in relation to body mass and hormonal changes
Kaur S, Nimmala S, Singhal V, Mitchell D, Pedreira C, Lauze M, Lee H, Stanford F, Bouxsein M, Bredella M, Misra M. Bone changes post-sleeve gastrectomy in relation to body mass and hormonal changes. European Journal Of Endocrinology 2023, 189: 346-354. PMID: 37633255, PMCID: PMC11188938, DOI: 10.1093/ejendo/lvad121.Peer-Reviewed Original ResearchConceptsSex hormone binding globulinTrabecular volumetric BMDABMD Z-scoresFree androgen indexNon-surgical controlsAreal bone mineral densityVolumetric BMDBMI z-scoreSleeve gastrectomyZ-scoreLean massModerate-to-severe obesityAssociated with bone lossAssociated with decreasesImpaired bone healthBone turnover markersBone mineral densityHigh-resolution peripheral quantitative CTPost sleeve gastrectomyMonths post-SGMicrofinite element analysisPeripheral quantitative CTSerum CTXTurnover markersPost-SGMale Runners With Lower Energy Availability Have Impaired Skeletal Integrity Compared to Nonathletes
Haines M, Kaur S, Scarff G, Lauze M, Gerweck A, Slattery M, Oreskovic N, Ackerman K, Tenforde A, Popp K, Bouxsein M, Miller K, Misra M. Male Runners With Lower Energy Availability Have Impaired Skeletal Integrity Compared to Nonathletes. The Journal Of Clinical Endocrinology & Metabolism 2023, 108: e1063-e1073. PMID: 37079740, PMCID: PMC10505543, DOI: 10.1210/clinem/dgad215.Peer-Reviewed Original ResearchConceptsBone mineral densityImpaired skeletal integrityMale runnersLean massCalcium intakeCaloric intakeRunning mileageSkeletal integrityBone mineral density Z-scoreLumbar spine BMD Z-scoreBSI riskTrabecular volumetric bone mineral densityImpaired bone mineral densitySpine BMD Z-scoreZ-scoreVolumetric bone mineral densityTibial failure loadBMD Z-scoresExercise energy expenditureInsufficient caloric intakeAppendicular lean massWeight-bearing activitiesBody mass indexTrabecular bone volume fractionEnergy expenditure
2022
RF18 | PSAT162 Male Runners Have Impaired Tibial Cortical Bone Integrity and Strength Compared to Non-athletes
Haines M, Kaur S, Scarff G, Lauze M, Gerweck A, Slattery M, Miller K, Misra M. RF18 | PSAT162 Male Runners Have Impaired Tibial Cortical Bone Integrity and Strength Compared to Non-athletes. Journal Of The Endocrine Society 2022, 6: a228-a228. PMCID: PMC9624774, DOI: 10.1210/jendso/bvac150.468.Peer-Reviewed Original ResearchTibial failure loadLow energy availabilityVolumetric BMDMale runnersLean massFemale athletesBone stress injuriesBone strengthImpaired bone microarchitectureTrabecular volumetric BMDCortical volumetric BMDWeight-bearing activitiesImpaired bone strengthCortical bone integrityEstimated bone strengthResolution peripheral quantitative CTMicrofinite element analysisPeripheral quantitative CTNon-athletesMale athletesBone outcomesEstradiol levelsSerum leptinCortical BMDLow leptinChanges in Sex Steroids and Enteric Peptides After Sleeve Gastrectomy in Youth in Relation to Changes in Bone Parameters
Nimmala S, Kaur S, Singhal V, Mitchell D, Stanford F, Bouxsein M, Lauze M, Huynh C, Pedreira C, Lee H, Bredella M, Misra M. Changes in Sex Steroids and Enteric Peptides After Sleeve Gastrectomy in Youth in Relation to Changes in Bone Parameters. The Journal Of Clinical Endocrinology & Metabolism 2022, 107: e3747-e3758. PMID: 35689793, PMCID: PMC9387701, DOI: 10.1210/clinem/dgac361.Peer-Reviewed Original ResearchConceptsBody mass indexFree androgen indexSleeve gastrectomyVolumetric BMDEnteric peptidesSex steroidsLean massModerate-to-severe obesityDual-energy X-ray absorptiometry measurementsMeasurements of areal bone mineral densityBody compositionAreal bone mineral densityZ-scoreAssociated with changesMeasures of volumetric BMDImpaired bone healthBone turnover markersABMD Z-scoresFasting peptide YYBone mineral densityPeripheral quantitative computed tomographyResolution peripheral quantitative computed tomographyTertiary-care hospitalQuantitative computed tomographyMicrofinite element analysis