2024
Association Between Restricting Symptoms and Disability After Critical Illness Among Older Adults.
Jain S, Han L, Gahbauer E, Leo-Summers L, Feder S, Ferrante L, Gill T. Association Between Restricting Symptoms and Disability After Critical Illness Among Older Adults. Critical Care Medicine 2024, 52: 1816-1827. PMID: 39298623, DOI: 10.1097/ccm.0000000000006427.Peer-Reviewed Original ResearchActivities of daily livingAssociated with increased disabilityDaily livingOlder adultsRestricting symptomsInstrumental activities of daily livingCommunity-living older adultsICU hospitalizationMultivariable Poisson regression modelsCommunity-living adultsOlder ICU survivorsAge of participantsPoisson regression modelsSurvive critical illnessCritical illnessQuality of lifeInstrumental activitiesICU survivorsProspective longitudinal studyLength of stayPost-ICUIncreased disabilityMonthly interviewsICU length of stayPre-ICUTrends in use of intensive care during hospitalizations at the end‐of‐life among older adults with advanced cancer
Jain S, Long J, Rao V, Law A, Walkey A, Prsic E, Lindenauer P, Krumholz H, Gross C. Trends in use of intensive care during hospitalizations at the end‐of‐life among older adults with advanced cancer. Journal Of The American Geriatrics Society 2024 PMID: 39090970, DOI: 10.1111/jgs.19119.Peer-Reviewed Original ResearchEnd-of-life hospitalizationsLife-sustaining treatmentEnd-of-lifeIntensity of careIn-hospital deathOlder adultsIntensive care unitAdvanced cancerRisk-adjusted hospitalEvaluate trendsIncreased intensity of careIntensive care unit useSEER-Medicare dataIntensive care unit careMultinomial regression modelsYear of diagnosisIntensive careHospital categoryMedicare beneficiariesSEER-MedicareHospitalization ratesCareCancer characteristicsNoninvasive ventilationHospitalSocial Determinants of Health and Delivery of Rehabilitation to Older Adults During ICU Hospitalization
Jain S, Murphy T, Falvey J, Leo-Summers L, O’Leary J, Zang E, Gill T, Krumholz H, Ferrante L. Social Determinants of Health and Delivery of Rehabilitation to Older Adults During ICU Hospitalization. JAMA Network Open 2024, 7: e2410713. PMID: 38728030, PMCID: PMC11087837, DOI: 10.1001/jamanetworkopen.2024.10713.Peer-Reviewed Original ResearchConceptsSocial determinants of healthDeterminants of healthOccupational therapyPhysical therapyOlder adultsRural residentsIntensive care unit hospitalizationRehabilitation deliveryIntensive care unitSocial determinantsSocioeconomic disadvantageNational Health and Aging Trends StudyDelivery of physical therapyIllness hospitalizationFactors associated with lower oddsDelivery of rehabilitationIn-hospital rehabilitationMitigate functional declineMedicaid eligibilityBurden of disabilityHigh school educationDual MedicareTrends StudyMedicare claimsLength of staySurvival, Function, and Cognition After Hospitalization in Long-Term Acute Care Hospitals
Jain S, Gan S, Nguyen O, Sudore R, Steinman M, Covinsky K, Makam A. Survival, Function, and Cognition After Hospitalization in Long-Term Acute Care Hospitals. JAMA Network Open 2024, 7: e2413309. PMID: 38805226, PMCID: PMC11134219, DOI: 10.1001/jamanetworkopen.2024.13309.Peer-Reviewed Original ResearchConceptsHealth and Retirement StudyLong-term acute care hospitalHealth and Retirement Study interviewsActivities of daily livingAcute care hospitalsOlder adultsMiddle-agedCognitive statusLong-term acute care hospital admissionCare hospitalCohort studyAcute illnessAssociated with lower riskIncreased likelihood of deathAdverse outcomesLikelihood of deathMultivariate logistic regressionReceipt of mechanical ventilationSevere impairmentDaily livingRetirement StudyRetrospective cohort studyMedicare claimsLee index scoresMain OutcomesHospital Variation in the Use of Intravenous Benzodiazepines for Sedation During Early Mechanical Ventilation
Jain S, Gershengorn H, Priya A, Walkey A, Burry L, Krumholz H, Wunsch H, Lindenauer P. Hospital Variation in the Use of Intravenous Benzodiazepines for Sedation During Early Mechanical Ventilation. 2024, a1095-a1095. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a1095.Peer-Reviewed Original ResearchHospital Variation in Delivery of Skilled Rehabilitation to Mechanically Ventilated Older Adults With Acute Respiratory Failure
Jimenez Ceja J, Zhang L, Lin Z, Walkey A, Krumholz H, Jain S. Hospital Variation in Delivery of Skilled Rehabilitation to Mechanically Ventilated Older Adults With Acute Respiratory Failure. 2024, a1096-a1096. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a1096.Peer-Reviewed Original ResearchRacial Differences in 1-Year Mortality after Hospitalization for Chronic Obstructive Pulmonary Disease in the United States.
Jain S, Priya A, Pekow P, Spitzer K, Walkey A, Opara I, Krumholz H, Lindenauer P. Racial Differences in 1-Year Mortality after Hospitalization for Chronic Obstructive Pulmonary Disease in the United States. Annals Of The American Thoracic Society 2024, 21: 585-594. PMID: 37943953, PMCID: PMC10995557, DOI: 10.1513/annalsats.202304-359oc.Peer-Reviewed Original ResearchChronic obstructive pulmonary diseaseChronic obstructive pulmonary disease hospitalizationsObstructive pulmonary diseaseMedicare beneficiariesWhite racePulmonary diseaseChronic obstructive pulmonary disease exacerbationsChronic obstructive pulmonary disease patientsObstructive pulmonary disease exacerbationsObstructive pulmonary disease patientsHospital-level clusteringPulmonary disease exacerbationsRetrospective cohort studyPulmonary disease patientsCox regression modelIndividual socioeconomic statusDisease exacerbationPulmonary rehabilitationCohort studyDischarge dispositionOverall mortalityIllness severityHospitalized populationCare factorsDisease patientsPatient Privacy and Data Provenance in Pulmonary and Critical Care Research Using Big Data.
Jain S, Krumholz H. Patient Privacy and Data Provenance in Pulmonary and Critical Care Research Using Big Data. Annals Of The American Thoracic Society 2024, 21: 538-540. PMID: 38259228, PMCID: PMC10995548, DOI: 10.1513/annalsats.202305-497ip.Peer-Reviewed Original ResearchAging, Race, and Health Disparities: Recommendations From the Research Centers Collaborative Network
Jain S, Bey G, Forrester S, Rahman-Filipiak A, Gonzalez N, Petrovsky D, Kritchevsky S, Brinkley T. Aging, Race, and Health Disparities: Recommendations From the Research Centers Collaborative Network. The Journals Of Gerontology Series B 2024, 79: gbae028. PMID: 38442186, PMCID: PMC11101762, DOI: 10.1093/geronb/gbae028.Peer-Reviewed Original ResearchConceptsHealth disparitiesHealth disparities researchAdverse health outcomesHealth equityDisparities researchHealth outcomesMitigate disparitiesRacial disparitiesEvidence baseCommunity engagementHealthy agingResearch Centers Collaborative NetworkIncreased participationResearch prioritiesDisparitiesHealthRacial comparisonsAgeRecommendationsRacePolicy implicationsCollaborative networksParticipantsPartnershipTraining
2023
Eye on the Prize: Patient Outcomes Research in Medical Education
Cooper A, Jain S, Santhosh L, Carlos W. Eye on the Prize: Patient Outcomes Research in Medical Education. ATS Scholar 2023, 5: 8-18. PMID: 38585575, PMCID: PMC10995853, DOI: 10.34197/ats-scholar.2023-0046ps.Peer-Reviewed Original ResearchDistressing Symptoms and Disability After Critical Illness Among Older Adults
Jain S, Han L, Gahbauer E, Leo-Summers L, Ferrante L, Gill T. Distressing Symptoms and Disability After Critical Illness Among Older Adults. 2023, a2888-a2888. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2888.Peer-Reviewed Original ResearchSocial Vulnerability and Delivery of In-hospital Rehabilitation Services to Older Adults With Critical Illness
Jain S, Murphy T, O'Leary Jr J, Leo-Summers L, Zang E, Falvey J, Gill T, Krumholz H, Ferrante L. Social Vulnerability and Delivery of In-hospital Rehabilitation Services to Older Adults With Critical Illness. 2023, a2889-a2889. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2889.Peer-Reviewed Original ResearchTrends in Utilization of ICU for Older Adults With Cancer at the End-of-Life
Jain S, Long J, Rao V, Law A, Walkey A, Lindenauer P, Prsic E, Krumholz H, Gross C. Trends in Utilization of ICU for Older Adults With Cancer at the End-of-Life. 2023, a1398-a1398. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1398.Peer-Reviewed Original ResearchPreexisting Care Needs and Long-Term Outcomes After Mechanical Ventilation: Are We Any Closer to Informing Treatment Choices for Older Adults?*
Jain S. Preexisting Care Needs and Long-Term Outcomes After Mechanical Ventilation: Are We Any Closer to Informing Treatment Choices for Older Adults?*. Critical Care Medicine 2023, 51: 683-685. PMID: 37052439, DOI: 10.1097/ccm.0000000000005827.Peer-Reviewed Original ResearchDifferences in international medical graduates’ letters of recommendation by gender in pulmonary and critical care medicine: a cohort analysis
Byrd K, Jain S, Choudhuri I, Çoruh B, McSparron J, Viglianti E. Differences in international medical graduates’ letters of recommendation by gender in pulmonary and critical care medicine: a cohort analysis. BMC Medical Education 2023, 23: 58. PMID: 36694194, PMCID: PMC9875522, DOI: 10.1186/s12909-023-04042-5.Peer-Reviewed Original Research
2022
Clin‐STAR corner: Recent practice‐changing studies at the interface of pulmonary and critical care medicine and geriatrics
Jain S, Witt L, Ferrante L. Clin‐STAR corner: Recent practice‐changing studies at the interface of pulmonary and critical care medicine and geriatrics. Journal Of The American Geriatrics Society 2022, 71: 705-710. PMID: 36536494, PMCID: PMC10023292, DOI: 10.1111/jgs.18196.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCritical care medicineCritical illnessPulmonary diseaseLung diseaseCare medicineRecent practice-changing clinical trialsChronic obstructive pulmonary diseaseOlder adultsAcute respiratory failurePractice-changing clinical trialsChronic lung diseaseChronic pulmonary diseaseObstructive pulmonary diseaseInterstitial lung diseasePractice-changing studiesGreater side effectsRespiratory failureAdverse outcomesClinical trialsObservational studySide effectsDiseaseIllnessAdultsMedicineWho Receives ICU Care during Times of Strain? Triage and the Potential for Racial Disparities
Jain S, Valley T. Who Receives ICU Care during Times of Strain? Triage and the Potential for Racial Disparities. Annals Of The American Thoracic Society 2022, 19: 1973-1974. PMID: 36454169, PMCID: PMC9743470, DOI: 10.1513/annalsats.202209-766ed.Peer-Reviewed Original ResearchWellness and Coping of Physicians Who Worked in ICUs During the Pandemic: A Multicenter Cross-Sectional North American Survey*
Burns KEA, Moss M, Lorens E, Jose EKA, Martin CM, Viglianti EM, Fox-Robichaud A, Mathews KS, Akgun K, Jain S, Gershengorn H, Mehta S, Han JE, Martin GS, Liebler JM, Stapleton RD, Trachuk P, Vranas KC, Chua A, Herridge MS, Tsang JLY, Biehl M, Burnham EL, Chen JT, Attia EF, Mohamed A, Harkins MS, Soriano SM, Maddux A, West JC, Badke AR, Bagshaw SM, Binnie A, Carlos WG, Çoruh B, Crothers K, D’Aragon F, Denson JL, Drover JW, Eschun G, Geagea A, Griesdale D, Hadler R, Hancock J, Hasmatali J, Kaul B, Kerlin MP, Kohn R, Kutsogiannis DJ, Matson SM, Morris PE, Paunovic B, Peltan ID, Piquette D, Pirzadeh M, Pulchan K, Schnapp LM, Sessler CN, Smith H, Sy E, Thirugnanam S, McDonald RK, McPherson KA, Kraft M, Spiegel M, Dodek PM, Society F. Wellness and Coping of Physicians Who Worked in ICUs During the Pandemic: A Multicenter Cross-Sectional North American Survey*. Critical Care Medicine 2022, 50: 1689-1700. PMID: 36300945, PMCID: PMC9668381, DOI: 10.1097/ccm.0000000000005674.Peer-Reviewed Original ResearchSubinternships in the Medical Intensive Care Unit: A Needs Assessment
Selvan K, Clark A, Walters R, Jain S, Kaul V, Richards J, Caverzagie K, Dallaghan G, Stewart N. Subinternships in the Medical Intensive Care Unit: A Needs Assessment. ATS Scholar 2022, 3: 352-357. PMID: 36312812, PMCID: PMC9585702, DOI: 10.34197/ats-scholar.2022-0019br.Peer-Reviewed Original ResearchSocial determinants of recovery
Jain S, Hauschildt K, Scheunemann L. Social determinants of recovery. Current Opinion In Critical Care 2022, 28: 557-565. PMID: 35993295, DOI: 10.1097/mcc.0000000000000982.Peer-Reviewed Original ResearchConceptsCritical illnessSocial determinantsCritical illness survivorsLong-term outcomesCaregiver burdenClinical careCognitive impairmentFinancial toxicityHealth systemIllnessMental healthNeighbourhood deprivationSocial factorsSocioeconomic statusHospitalizationSocial supportHealthIndividual factorsFactorsDeterminantsRecoveryCliniciansSurvivorsImpairmentCare