2022
New mechanism of chromatin compartmentalization by BRD2
Cheng Y, Wang S. New mechanism of chromatin compartmentalization by BRD2. Trends In Genetics 2022, 38: 1197-1198. PMID: 35811175, DOI: 10.1016/j.tig.2022.06.016.Peer-Reviewed Original Research
2020
Chromatin Tracing: Imaging 3D Genome and Nucleome
Hu M, Wang S. Chromatin Tracing: Imaging 3D Genome and Nucleome. Trends In Cell Biology 2020, 31: 5-8. PMID: 33191055, PMCID: PMC8094612, DOI: 10.1016/j.tcb.2020.10.006.Peer-Reviewed Original Research
2016
Spatial organization of chromatin domains and compartments in single chromosomes
Wang S, Su JH, Beliveau BJ, Bintu B, Moffitt JR, Wu CT, Zhuang X. Spatial organization of chromatin domains and compartments in single chromosomes. Science 2016, 353: 598-602. PMID: 27445307, PMCID: PMC4991974, DOI: 10.1126/science.aaf8084.Peer-Reviewed Original ResearchConceptsIndividual chromosomesChromatin domainsX chromosomeNumerous genomic regionsSpatial organizationInactive X chromosomeGenome functionChromatin organizationGenomic regionsFractal globule modelSingle chromosomePolarized mannerChromosomesDifferent foldingTADCompartmentsAutosomesChromatinDomainTADsFoldingRegulationCapture studies