2012
Adaptive Evolution and the Birth of CTCF Binding Sites in the Drosophila Genome
Ni X, Zhang YE, Nègre N, Chen S, Long M, White KP. Adaptive Evolution and the Birth of CTCF Binding Sites in the Drosophila Genome. PLOS Biology 2012, 10: e1001420. PMID: 23139640, PMCID: PMC3491045, DOI: 10.1371/journal.pbio.1001420.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, BiologicalAnimalsBase SequenceBinding SitesCCCTC-Binding FactorConserved SequenceDrosophilaDrosophila ProteinsEvolution, MolecularGenetic DriftGenetics, PopulationGenome, InsectOligonucleotide Array Sequence AnalysisPhylogenyProtein BindingRepressor ProteinsSelection, GeneticSpecies SpecificityTime FactorsConceptsCTCF binding siteDrosophila melanogasterNew genesCis-regulatory DNA sequencesGene expressionSpecies of DrosophilaGenome-wide bindingSignatures of selectionGenomes of humansComparative gene expression profilingGenome sequence dataRecent common ancestorGene expression profilingBinding sitesExpression divergenceGenome evolutionAdaptive evolutionDrosophila genomeDrosophila simulansEvolutionary ratesCTCF bindingCTCF proteinEvolutionary distanceNew CTCFCommon ancestor
2011
Highly Tissue Specific Expression of Sphinx Supports Its Male Courtship Related Role in Drosophila melanogaster
Chen Y, Dai H, Chen S, Zhang L, Long M. Highly Tissue Specific Expression of Sphinx Supports Its Male Courtship Related Role in Drosophila melanogaster. PLOS ONE 2011, 6: e18853. PMID: 21541324, PMCID: PMC3082539, DOI: 10.1371/journal.pone.0018853.Peer-Reviewed Original ResearchMeSH KeywordsAnimal StructuresAnimalsBase PairingBase SequenceBrainConserved SequenceCourtshipDrosophila melanogasterFemaleGene Expression ProfilingGene Expression RegulationGenome, InsectGreen Fluorescent ProteinsMaleMolecular Sequence DataMutationOrgan SpecificityPeripheral Nervous SystemPromoter Regions, GeneticRNA, UntranslatedSexual Behavior, AnimalTransformation, GeneticConceptsDrosophila melanogasterBp regionCourtship behaviorNon-coding RNA genesWhole genome expression profilingBp upstream regionTissue-specific expressionGenome expression profilingMale courtship behaviorMale accessory glandsMelanogaster subgroupDrosophila speciesD. virilisRNA genesGene categoriesProtein functionKnockout mutationsWing hairsMale courtshipTarget genesExpression profilingGFP signalNegative regulatorEnhancer elementsExpression signals
2003
RNA-dependent RNA polymerase gene sequence from foot-and-mouth disease virus in Hong Kong
Chen X, Feng Q, Wu Z, Liu Y, Huang K, Shi R, Chen S, Lu W, Ding M, Collins R, Fung Y, Lau L, Yu A, Chen J. RNA-dependent RNA polymerase gene sequence from foot-and-mouth disease virus in Hong Kong. Biochemical And Biophysical Research Communications 2003, 308: 899-905. PMID: 12927804, DOI: 10.1016/s0006-291x(03)01511-0.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid MotifsAmino Acid SequenceBase SequenceCloning, MolecularConserved SequenceDNA-Directed RNA PolymerasesFoot-and-Mouth Disease VirusGenetic VariationHong KongModels, GeneticMolecular Sequence DataMutationPhylogenyProtein Structure, TertiaryReverse Transcriptase Polymerase Chain ReactionRNA-Dependent RNA PolymeraseRNA, ViralSequence Analysis, DNASequence Homology, Amino AcidConceptsRNA-dependent RNA polymerase gene sequencesNucleotide sequenceRNA polymerase gene sequencesViral RNA-dependent RNA polymeraseRNA-dependent RNA polymeraseAmino acid sequenceAmino acid residuesMouth disease virusPolymerase gene sequencesCommon ancestorEvolutionary treeRNA polymeraseGene sequencesSequence comparisonAcid sequenceSame geneN-terminusDisease virusAcid residuesGenesFunctional relevanceRepresentative isolatesHost immune systemFMDV isolatesHKN/2002