2023
Functional Characterization of MC4R Variants in Chinese Morbid Obese Patients and Weight Loss after Bariatric Surgery
Gong Y, Wu Q, Huang S, Fu Z, Ye J, Liu R, Lin S, Guan W, Yang N, Li J, Liang H, Zhou H. Functional Characterization of MC4R Variants in Chinese Morbid Obese Patients and Weight Loss after Bariatric Surgery. Advanced Biology 2023, 7: e2300007. PMID: 37140139, DOI: 10.1002/adbi.202300007.Peer-Reviewed Original ResearchConceptsMorbid obese patientsMC4R variantsObese patientsWeight lossExcess weight lossCommon genetic causeBariatric surgeryMetabolic surgeryObesity cohortObese populationMonths postsurgeryPatientsSurgery proceduresPersonalized treatmentFunction variantsSurgeryGenetic causeG233V103IR165WCohortLarge size cohortObesityPostsurgeryEWL
2021
Effectiveness of companion-intensive multi-aspect weight management in Chinese adults with obesity: a 6-month multicenter randomized clinical trial
Jiang W, Huang S, Ma S, Gong Y, Fu Z, Zhou L, Hu W, Mao G, Ma Z, Yang L, Tang G, Sun X, Zhang P, Bai J, Chen L, Shi B, Ye X, Zhou H. Effectiveness of companion-intensive multi-aspect weight management in Chinese adults with obesity: a 6-month multicenter randomized clinical trial. Nutrition & Metabolism 2021, 18: 17. PMID: 33536048, PMCID: PMC7856778, DOI: 10.1186/s12986-020-00511-6.Peer-Reviewed Original ResearchNon-alcoholic fatty liver disease (NAFLD) scoreBody mass indexBody fat massVisceral fat areaWeight managementSignificant weight lossTotal cholesterolChinese adultsClinical trialsWeight lossBody compositionVisceral fat area ratioChinese Clinical Trial RegistryMeal replacementMonthly faceLiver Disease scoreClinical Trials RegistryEarly lifestyle interventionsObese Chinese adultsSkeletal muscle massFat area ratioOnline InstructionsHOMA-IRLifestyle interventionHighest tertile