2003
Constitutive expression of cytotoxic proteases and down-regulation of protease inhibitors in LGL leukemia.
Kothapalli R, Bailey R, Kusmartseva I, Mane S, Epling-Burnette P, Loughran T. Constitutive expression of cytotoxic proteases and down-regulation of protease inhibitors in LGL leukemia. International Journal Of Oncology 2003, 22: 33-9. PMID: 12469182, DOI: 10.3892/ijo.22.1.33.Peer-Reviewed Original ResearchConceptsRNase protection assaysGene expressionPeripheral blood mononuclear cellsGroup of genesDifferential gene expressionNormal peripheral blood mononuclear cellsBlood mononuclear cellsNorthern blot analysisLGL leukemiaSmall subunitCaspase-8Protein perforinConstitutive expressionMicroarray technologyMononuclear cellsCytotoxic proteasesGenesProtection assaysCysteine proteinasesLarge granular lymphocyte leukemiaBlot analysisLGL leukemia patientsGranular lymphocyte leukemiaAlpha-1 antitrypsinExpression
2002
Microarray results: how accurate are they?
Kothapalli R, Yoder S, Mane S, Loughran T. Microarray results: how accurate are they? BMC Bioinformatics 2002, 3: 22. PMID: 12194703, PMCID: PMC126254, DOI: 10.1186/1471-2105-3-22.Peer-Reviewed Original ResearchAllelesCells, CulturedComputational BiologyDNA, ComplementaryGene Expression ProfilingGene Expression Regulation, EnzymologicGene Expression Regulation, NeoplasticGenes, NeoplasmGranzymesHumansLeukemia, LymphoidLeukocytes, MononuclearOligonucleotide Array Sequence AnalysisReproducibility of ResultsRNA, MessengerRNA, NeoplasmSensitivity and SpecificitySerine Endopeptidases