2013
A preliminary study on the effect of combined nicotine replacement therapy on alcohol responses and alcohol self‐administration
Udo T, Harrison EL, Shi J, Tetrault J, McKee SA. A preliminary study on the effect of combined nicotine replacement therapy on alcohol responses and alcohol self‐administration. American Journal On Addictions 2013, 22: 590-597. PMID: 24131167, PMCID: PMC3934424, DOI: 10.1111/j.1521-0391.2013.12014.x.Peer-Reviewed Original ResearchConceptsSelf-administration periodNicotine nasal sprayHeavy drinking smokersNasal sprayNicotine patchAlcohol responsesPriming drinkSerum nicotine levelsPlacebo-controlled studyNicotine replacement therapySubjective alcohol responsesPositive subjective responsesNumber of drinksPlacebo administrationReplacement therapyPriming doseSmoking relapseAlcohol consumptionPlacebo conditionPatch applicationNicotine levelsClinical settingPilot studySmokersSubjective responses
2011
Effects of pregabalin on smoking behavior, withdrawal symptoms, and cognitive performance in smokers
Herman AI, Waters AJ, McKee SA, Sofuoglu M. Effects of pregabalin on smoking behavior, withdrawal symptoms, and cognitive performance in smokers. Psychopharmacology 2011, 220: 611-617. PMID: 21947318, PMCID: PMC3654651, DOI: 10.1007/s00213-011-2507-x.Peer-Reviewed Original ResearchConceptsPregabalin treatmentSmoking behaviorWithdrawal symptomsTreatment periodAd lib smoking behaviorCognitive performanceEffect of pregabalinTobacco withdrawal symptomsDays of treatmentPregabalin effectCrossover studyWashout periodNicotine withdrawalGABA neurotransmissionNicotine rewardSmoking periodTobacco withdrawalAbstinent smokersBrain glutamateClinical studiesNicotine addictionSmokersPregabalinConclusionsThese findingsGABA analogues