2019
The Role of Volume Regulation and Thermoregulation in AKI during Marathon Running
Mansour SG, Martin TG, Obeid W, Pata RW, Myrick KM, Kukova L, Jia Y, Bjornstad P, El-Khoury JM, Parikh CR. The Role of Volume Regulation and Thermoregulation in AKI during Marathon Running. Clinical Journal Of The American Society Of Nephrology 2019, 14: 1297-1305. PMID: 31413064, PMCID: PMC6730516, DOI: 10.2215/cjn.01400219.Peer-Reviewed Original ResearchConceptsCore body temperatureBody temperaturePercent of runnersAcute tubular injuryPlasma copeptin concentrationsMajority of runnersContinuous core body temperatureAKIN criteriaDays postmarathonPrior marathonsTransient AKICopeptin concentrationsTubular injuryInjury biomarkersPrimary outcomeProspective cohortNephron damageNegative sodiumUrine microscopyVolume lossUrine sedimentAKIAbstractTextSweat sodiumCopeptin
2017
Kidney Injury and Repair Biomarkers in Marathon Runners
Mansour SG, Verma G, Pata RW, Martin TG, Perazella MA, Parikh CR. Kidney Injury and Repair Biomarkers in Marathon Runners. American Journal Of Kidney Diseases 2017, 70: 252-261. PMID: 28363731, PMCID: PMC5526736, DOI: 10.1053/j.ajkd.2017.01.045.Peer-Reviewed Original ResearchConceptsCreatinine levelsDay 0Kidney injuryTubular injuryUrine albuminSerum creatinineKidney functionUrine biomarkersBiomarker levelsSerum creatine kinase levelsMarathon runnersAKI Network criteriaAKI stage 1Stage 1 AKISerum creatinine levelsRenal tubular epithelial cellsLimited clinical dataCreatine kinase levelsTubular epithelial cellsDL increaseMean ageMicroscopy scoreGranular castsClinical dataObservational study