Urine Injury Biomarkers Are Not Associated With Kidney Transplant Failure.
Koyawala N, Reese PP, Hall IE, Jia Y, Thiessen-Philbrook HR, Mansour SG, Doshi MD, Akalin E, Bromberg JS, Harhay MN, Mohan S, Muthukumar T, Schröppel B, Singh P, Weng FL, Parikh CR. Urine Injury Biomarkers Are Not Associated With Kidney Transplant Failure. Transplantation 2020, 104: 1272-1279. PMID: 31568213, PMCID: PMC7384615, DOI: 10.1097/tp.0000000000002948.Peer-Reviewed Original ResearchConceptsAcute kidney injuryDonor Acute Kidney InjuryGraft failureInjury biomarkersSerum creatinineGraft outcomeKidney injuryComposite outcomeDeath-censored graft failureRisk of GFKidney injury molecule-1Cox proportional hazards modelLiver-type fatty acidSimilar allograft survivalStructural kidney damageKidney transplant recipientsInjury molecule-1Kidney transplant failureGlomerular filtration rateProportional hazards modelAKI kidneysAllograft survivalTransplant recipientsChart reviewNeutrophil gelatinaseAssociation of Deceased Donor Acute Kidney Injury With Recipient Graft Survival
Liu C, Hall IE, Mansour S, Philbrook H, Jia Y, Parikh CR. Association of Deceased Donor Acute Kidney Injury With Recipient Graft Survival. JAMA Network Open 2020, 3: e1918634. PMID: 31913491, PMCID: PMC6991314, DOI: 10.1001/jamanetworkopen.2019.18634.Peer-Reviewed Original ResearchConceptsDonor Acute Kidney InjuryAcute kidney injuryRecipient graft survivalDeath-censored graft failureCause graft failureAKI kidneysDeceased donorsGraft failureGraft survivalOrgan procurement organizationsAKI statusGraft functionKidney injuryPrimary nonfunctionMean agePropensity score-matched cohort studyTerminal serum creatinine levelPropensity score-matched analysisFollowing secondary outcomesDelayed graft functionSerum creatinine levelsProcurement organizationsDeceased donor kidneysDates of analysisAKI stage