Two types of precursor cells in a multipotential hematopoietic cell line
Ye ZJ, Kluger Y, Lian Z, Weissman SM. Two types of precursor cells in a multipotential hematopoietic cell line. Proceedings Of The National Academy Of Sciences Of The United States Of America 2005, 102: 18461-18466. PMID: 16352715, PMCID: PMC1317970, DOI: 10.1073/pnas.0509314102.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, CD34Cell DifferentiationCell LineGene Expression ProfilingGene Expression RegulationGlobinsHematopoietic Stem CellsMiceMultipotent Stem CellsOligonucleotide Array Sequence AnalysisPhosphorylationProtein BindingProto-Oncogene Proteins c-kitReceptors, Interleukin-3Transcription FactorsConceptsMultipotential hematopoietic cell linePrecursor cellsBeta-globin transcriptionCell linesMultipotential cell lineLocus control region hypersensitive site-2CD34- populationHypersensitive site 2Hematopoietic cell linesStem cell factor receptorPresence of SCFHematopoietic differentiationCell factor receptorDevelopmental transitionsNormal developmental transitionsCytokines IL-3Growth responseCell surface markersFactor receptorIL-3Mixed populationSite 2CellsSurface markersDifferent roles