PULMONARY TOXICITY OF SIMULATED LUNAR AND MARTIAN DUSTS IN MICE: I. HISTOPATHOLOGY 7 AND 90 DAYS AFTER INTRATRACHEAL INSTILLATION
Lam CW, James JT, McCluskey R, Cowper S, Balis J, Muro-Cacho C. PULMONARY TOXICITY OF SIMULATED LUNAR AND MARTIAN DUSTS IN MICE: I. HISTOPATHOLOGY 7 AND 90 DAYS AFTER INTRATRACHEAL INSTILLATION. Inhalation Toxicology 2002, 14: 901-916. PMID: 12396402, DOI: 10.1080/08958370290084683.Peer-Reviewed Original ResearchConceptsParticle-laden macrophagesPeribronchiolar inflammationLung lesionsPulmonary toxicityChronic pulmonary inflammationChronic inflammatory lesionsEvidence of inflammationAcute inflammatory responseNumber of macrophagesFocal alveolitisLung injurySeptal thickeningPulmonary inflammationInflammatory lesionsMild fibrosisExamination 7Chronic mildInflammatory responseAlveolitisFibrosisInflammationLungOverall severityMSS groupMice