2013
Evolution of Enterohemorrhagic Escherichia coli O26 Based on Single-Nucleotide Polymorphisms
Bletz S, Bielaszewska M, Leopold S, Köck R, Witten A, Schuldes J, Zhang W, Karch H, Mellmann A. Evolution of Enterohemorrhagic Escherichia coli O26 Based on Single-Nucleotide Polymorphisms. Genome Biology And Evolution 2013, 5: 1807-1816. PMID: 24105689, PMCID: PMC3814194, DOI: 10.1093/gbe/evt136.Peer-Reviewed Original ResearchMeSH KeywordsEnterohemorrhagic Escherichia coliEscherichia coli InfectionsEvolution, MolecularHemolytic-Uremic SyndromeHumansPhylogenyPolymorphism, Single NucleotideConceptsWhole-genome shotgun sequencing
2011
Intestinal damage in enterohemorrhagic Escherichia coli infection
Békássy Z, Calderon Toledo C, Leoj G, Kristoffersson A, Leopold S, Perez M, Karpman D. Intestinal damage in enterohemorrhagic Escherichia coli infection. Pediatric Nephrology 2011, 26: 2059-2071. PMID: 20809220, DOI: 10.1007/s00467-010-1616-9.Peer-Reviewed Original ResearchConceptsEnterohemorrhagic Escherichia coli infectionEscherichia coli infectionTUNEL-positive cellsIntestinal injuryIntestinal damageColi infectionSevere symptomsType III secretion effectorsAbundant TUNEL-positive cellsC3H/HeN micePresence of Stx2Mucosal cell deathMore TUNEL-positive cellsShiga toxin 2Fecal bacterial countsBacterial virulence factorsPresence of intiminSigmoid colonHeN miceDistal colonEHEC infectionMore symptomsToxin 2Strain 87Symptoms