2013
Lineage and Genogroup-Defining Single Nucleotide Polymorphisms of Escherichia coli O157:H7
Jung W, Bono J, Clawson M, Leopold S, Shringi S, Besser T. Lineage and Genogroup-Defining Single Nucleotide Polymorphisms of Escherichia coli O157:H7. Applied And Environmental Microbiology 2013, 79: 7036-7041. PMID: 24014531, PMCID: PMC3811523, DOI: 10.1128/aem.02173-13.Peer-Reviewed Original ResearchConceptsSingle nucleotide polymorphismsNew sequencing dataNucleotide polymorphismsSequencing dataImportant reservoir hostsLineagesE. coli O157Typing panelZoonotic human pathogenColi O157H7 genotypesHuman pathogensRelevant lineagesLineage groupsReservoir hostsHuman clinical isolatesCattle isolatesBovine sourcesSNPsEscherichia coli O157IsolatesPolymorphismStx genesGenogroupsH7
2011
Thomas Whittam, Shiga Toxin‐Producing Escherichia coli, and the Clinical Consequences of Clonality
Leopold S, Tarr P. Thomas Whittam, Shiga Toxin‐Producing Escherichia coli, and the Clinical Consequences of Clonality. 2011, 257-272. DOI: 10.1128/9781555817114.ch15.Peer-Reviewed Original ResearchMicrobial evolutionE. coliSevere human diseasesPhylogenetic referenceGenetic analysisHuman diseasesVirulence traitsEscherichia coliToxin genesColiMinor groupEnteric pathogenicityShiga toxin genesOne's understandingE. coli O157CladeColi O157GenesClonalityEvolutionTraitsSpeciesWhittamPathogenicityShiga toxin-producing E. coli
2010
Further evidence of constrained radiation in the evolution of pathogenic Escherichia coli O157:H7
Leopold S, Shaikh N, Tarr P. Further evidence of constrained radiation in the evolution of pathogenic Escherichia coli O157:H7. Infection Genetics And Evolution 2010, 10: 1282-1285. PMID: 20691811, PMCID: PMC3742067, DOI: 10.1016/j.meegid.2010.07.021.Peer-Reviewed Original ResearchMeSH KeywordsBacterial Typing TechniquesBase SequenceBiological EvolutionDNA, BacterialEscherichia coliEscherichia coli O157Escherichia coli ProteinsEvolution, MolecularGene ExpressionGenetic VariationGenome, BacterialGenomicsGenotypeHumansMutationO AntigensPolymerase Chain ReactionPolymorphism, Single NucleotideRecombination, GeneticSequence Analysis, DNAShiga ToxinsVirulence