2020
Peri‐implantation cytokine profile differs between singleton and twin IVF pregnancies
Simpson S, Kaislasuo J, Peng G, Aldo P, Paidas M, Guller S, Mor G, Pal L. Peri‐implantation cytokine profile differs between singleton and twin IVF pregnancies. American Journal Of Reproductive Immunology 2020, 85: e13348. PMID: 32946159, PMCID: PMC8221280, DOI: 10.1111/aji.13348.Peer-Reviewed Original ResearchConceptsMaternal serum levelsSerum levelsSingleton gestationsIL-10Twin pregnanciesC motif chemokine ligand 10General immune reactionTwin IVF pregnanciesProspective longitudinal cohortSerum cytokine concentrationsAcademic fertility centerSerial serum samplesChemokine ligand 10Implantation phaseAnti-angiogenic roleSingleton conceptionsCXCL10 levelsIVF pregnanciesIVF-ETCytokine concentrationsInterleukin-10Fertility centerSerum concentrationsTumor necrosisLongitudinal cohort
2019
IL‐10 to TNFα ratios throughout early first trimester can discriminate healthy pregnancies from pregnancy losses
Kaislasuo J, Simpson S, Petersen JF, Peng G, Aldo P, Lokkegaard E, Paidas M, Pal L, Guller S, Mor G. IL‐10 to TNFα ratios throughout early first trimester can discriminate healthy pregnancies from pregnancy losses. American Journal Of Reproductive Immunology 2019, 83: e13195. PMID: 31585488, PMCID: PMC8295882, DOI: 10.1111/aji.13195.Peer-Reviewed Original ResearchMeSH KeywordsAbortion, SpontaneousAdultCohort StudiesFemaleFertilization in VitroHumansInterleukin-10PregnancyPregnancy Trimester, FirstTumor Necrosis Factor-alphaConceptsWeeks of gestationIL-10Pregnancy lossHealthy pregnancyFirst trimesterTNFα ratioNormal pregnancySymptoms of miscarriageIL-10 concentrationsProspective longitudinal cohortEarly first trimesterFirst trimester lossImplantation dayIVF cohortImmunological balanceSerum levelsViable pregnancySerial bloodGestation weeksTNFα concentrationsEarly immunomodulationLongitudinal cohortEmbryo implantationPregnancySingle time point