Urinary angiogenic factors cluster hypertensive disorders and identify women with severe preeclampsia
Buhimschi CS, Norwitz ER, Funai E, Richman S, Guller S, Lockwood CJ, Buhimschi IA. Urinary angiogenic factors cluster hypertensive disorders and identify women with severe preeclampsia. American Journal Of Obstetrics And Gynecology 2005, 192: 734-741. PMID: 15746665, DOI: 10.1016/j.ajog.2004.12.052.Peer-Reviewed Original ResearchConceptsVascular endothelial growth factorSevere preeclampsiaHypertensive disordersHypertensive womenUrinary levelsUrinary outputSFlt-1Soluble fms-like tyrosine kinase-1Fms-like tyrosine kinase-1Antiangiogenic factors sFlt-1Growth factorSFlt-1 concentrationsHealthy pregnant controlsPlacental growth factorTime of enrollmentTyrosine kinase-1Urinary protein measurementsEndothelial growth factorClinical preeclampsiaProteinuric womenPlGF levelsNonpregnant womenPlGF ratioPregnant controlsGestational age