2009
ORIGINAL ARTICLE: Regulation of Nod1 and Nod2 in First Trimester Trophoblast Cells
Mulla MJ, Yu AG, Cardenas I, Guller S, Panda B, Abrahams VM. ORIGINAL ARTICLE: Regulation of Nod1 and Nod2 in First Trimester Trophoblast Cells. American Journal Of Reproductive Immunology 2009, 61: 294-302. PMID: 19260860, DOI: 10.1111/j.1600-0897.2009.00694.x.Peer-Reviewed Original ResearchMeSH KeywordsApoptosisBenzamidesCells, CulturedCytokinesDiaminopimelic AcidFemaleGene Expression Regulation, DevelopmentalHumansLipopolysaccharidesNF-kappa BNod1 Signaling Adaptor ProteinNod2 Signaling Adaptor ProteinPregnancyPregnancy Trimester, FirstSequence DeletionSignal TransductionThiazolesToll-Like Receptor 4TransgenesTrophoblastsConceptsFirst trimester trophoblast cellsTrophoblast cellsExpression of NOD1Cytoplasmic pattern recognition receptorsProduction of cytokinesNOD2 mRNA expressionPattern recognition receptorsNOD2 expressionCytokine responsesInflammatory responseNOD2 activationNOD1 activationNFkappaB inhibitorRecognition receptorsNOD1Nod1 stimulationNOD2Bacterial lipopolysaccharideMRNA expressionTLR4LipopolysaccharideNFkappaB pathwayRT-PCRBacterial peptidesTrophoblast
2002
Regulation of Plasminogen Activator Inhibitor (PAI)-1 Expression in a Human Trophoblast Cell Line by Glucocorticoid (GC) and Transforming Growth Factor (TGF)-β
Ma Y, Ryu JS, Dulay A, Segal M, Guller S. Regulation of Plasminogen Activator Inhibitor (PAI)-1 Expression in a Human Trophoblast Cell Line by Glucocorticoid (GC) and Transforming Growth Factor (TGF)-β. Placenta 2002, 23: 727-734. PMID: 12398812, DOI: 10.1053/plac.2002.0863.Peer-Reviewed Original ResearchConceptsHTR-8/SVneo cellsIntrauterine growth restrictionPAI-2 levelsPAI-1 expressionPlasminogen activator inhibitorActivator inhibitorGrowth factorHuman trophoblast cell linePAI-1 levelsTrophoblast cell lineTransforming Growth FactorTGF-beta treatmentTGF-beta effectsPAI-1 proteinFibrin depositionGrowth restrictionDEX treatmentSynthetic glucocorticoidGlucocorticoidsPAI-1Regulation of fibrinolysisDexamethasoneTGF betaExcessive productionMRNA expression
1992
Growth hormone and fibronectin expression in 3T3 preadipose cells.
Guller S, Allen D, Corin R, Lockwood C, Sonenberg M. Growth hormone and fibronectin expression in 3T3 preadipose cells. Endocrinology 1992, 130: 2609-2616. DOI: 10.1210/en.130.5.2609.Peer-Reviewed Original ResearchInsulin-like growth factor-1Growth factor-1Fibronectin expressionGH actionPreadipose cellsFactor 1Function of GHFibronectin protein expressionLevels of fibronectin mRNASerum-free mediumFibronectin messenger RNAGH treatmentExtracellular matrixFibronectin levelsWestern blot analysisDose-dependentlyDay 1GH effectsGrowth hormoneFibronectin mRNAMRNA expressionProtein expressionGlycerol-3-phosphate dehydrogenase activityImmunoprecipitation studiesControl cells