2022
Microbe Profile: Wigglesworthia glossinidia: the tsetse fly’s significant other
Weiss BL, Rio RVM, Aksoy S. Microbe Profile: Wigglesworthia glossinidia: the tsetse fly’s significant other. Microbiology 2022, 168: 001242. PMID: 36129743, PMCID: PMC10723186, DOI: 10.1099/mic.0.001242.Peer-Reviewed Original ResearchConceptsPhysiological homeostasisNutritional roleEssential nutritional roleUnique physiological adaptationsTsetse fliesFly microbiotaWigglesworthia glossinidiaObligate mutualistsHost fitnessAncient associationParasitic trypanosomesLarval periodPhysiological adaptationsFitness outcomesTsetse's abilityAntimicrobial responsesImmune systemAmidasesFliesMicrobiotaMutualistsWigglesworthiaEndosymbiontsGenomeB vitamins
2015
Wigglesworthia
Aksoy S. Wigglesworthia. 2015, 1-6. DOI: 10.1002/9781118960608.gbm01172.Peer-Reviewed Original ResearchTypical Gram-negative cell wallGram-negative cell wallHost insect speciesInsect host speciesMilk gland secretionsInner membrane structureObligate intracellular organismsPrimary endosymbiontDifferentiated epithelial cellsInsect speciesIntrauterine larvaeS-symbiontsWigglesworthiaHost speciesLack flagellaAncient associationBiosynthetic pathwayAdult fliesMidgut tissueSpecies displayCell wallBinary fissionEndosymbiontsAposymbiotic hostsAnterior midgut
2011
Tsetse Immune System Maturation Requires the Presence of Obligate Symbionts in Larvae
Weiss BL, Wang J, Aksoy S. Tsetse Immune System Maturation Requires the Presence of Obligate Symbionts in Larvae. PLOS Biology 2011, 9: e1000619. PMID: 21655301, PMCID: PMC3104962, DOI: 10.1371/journal.pbio.1000619.Peer-Reviewed Original ResearchConceptsIntrauterine larvaeBeneficial microbial symbiontsSpecific host phenotypesMilk gland secretionsHost physiological processesCo-evolutionary adaptationMicrobial symbiontsWigglesworthia glossinidiaObligate mutualistsHost phenotypePhysiological processesImmune system homeostasisWigglesworthiaTsetse fliesImportant functionsGland secretionSystem homeostasisFliesGlossina morsitansMutualistsSymbiontsDietary supplementationLarvaeHomeostasisPhenotype
2001
A novel application of gene arrays: Escherichia coli array provides insight into the biology of the obligate endosymbiont of tsetse flies
Akman L, Aksoy S. A novel application of gene arrays: Escherichia coli array provides insight into the biology of the obligate endosymbiont of tsetse flies. Proceedings Of The National Academy Of Sciences Of The United States Of America 2001, 98: 7546-7551. PMID: 11404467, PMCID: PMC34705, DOI: 10.1073/pnas.131057498.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBacterial ProteinsDNA MethylationDNA ReplicationDNA, BacterialDNA, ComplementaryEnterobacteriaceaeEscherichia coliGenome, BacterialMolecular Sequence DataNucleic Acid HybridizationOligonucleotide Array Sequence AnalysisProtein BiosynthesisSymbiosisTranscription, GeneticTsetse FliesConceptsObligate endosymbiontsComplete genome sequence dataGene arrayBiosynthesis of cofactorsE. coli genesGenome sequence dataTsetse fliesFacultative anaerobic organismsObligate symbiontsOrthologous genesWigglesworthia glossinidiaSmall genomesGenome sizeSymbiotic associationGenome informationDNA replicationRelated organismsColi geneSymbiotic lifeSequence dataWigglesworthiaGene productsExpression analysisTransport proteinsExpression profiles