Lipid metabolism dysfunction following symbiont elimination is linked to altered Kennedy pathway homeostasis
Attardo G, Benoit J, Michalkova V, Kondragunta A, Baumann A, Weiss B, Malacrida A, Scolari F, Aksoy S. Lipid metabolism dysfunction following symbiont elimination is linked to altered Kennedy pathway homeostasis. IScience 2023, 26: 107108. PMID: 37534171, PMCID: PMC10391724, DOI: 10.1016/j.isci.2023.107108.Peer-Reviewed Original ResearchKennedy pathwayObligate endosymbiotic bacteriaViviparous tsetse flyLipid metabolismEarly developmental stagesInsect reproductionEndosymbiotic bacteriaSymbiotic bacteriaLipid biosynthesisPathway homeostasisSymbiont eliminationFunctional validationExperimental removalPhosphatidylcholine biosynthesisDevelopmental stagesProper functionTsetse fliesBiosynthesisLipid metabolism dysfunctionImpaired lipid metabolismMetabolismBacteriaPathwayMetabolism dysfunctionSymbionts