2022
Hyperammonemia syndrome in immunosuppressed individuals
Roberts SC, Malik W, Ison MG. Hyperammonemia syndrome in immunosuppressed individuals. Current Opinion In Infectious Diseases 2022, 35: 262-268. PMID: 35665721, PMCID: PMC9179651, DOI: 10.1097/qco.0000000000000828.Peer-Reviewed Original ResearchMeSH KeywordsHumansHyperammonemiaImmunocompromised HostSyndromeTransplant RecipientsUreaplasmaUreaplasma InfectionsConceptsLung transplant recipientsHyperammonemia syndromeUreaplasma sppTransplant recipientsImmunosuppressed individualsSolid organ transplant populationLung transplant donorsOrgan transplant populationPeri-transplant periodAppropriate antimicrobial therapyUrease-producing organismsHigh mortality rateTransplant populationTransplant donorsClinical manifestationsFatal conditionAntimicrobial therapySurveillance studyMortality rateSystemic infectionSyndromeDonor colonizationAntibiotic resistanceRapid diagnosticsRecipients
2020
Impact of Screening and Treatment of Ureaplasma species on Hyperammonemia Syndrome in Lung Transplant Recipients: A Single Center Experience
Roberts SC, Bharat A, Kurihara C, Tomic R, Ison MG. Impact of Screening and Treatment of Ureaplasma species on Hyperammonemia Syndrome in Lung Transplant Recipients: A Single Center Experience. Clinical Infectious Diseases 2020, 73: e2531-e2537. PMID: 33068392, PMCID: PMC8563172, DOI: 10.1093/cid/ciaa1570.Peer-Reviewed Original ResearchConceptsLung transplant recipientsLung transplantUreaplasma sppHyperammonemia syndromePolymerase chain reactionTransplant recipientsUreaplasma speciesSingle-center experienceBronchoalveolar lavage cultureRecipients of organsNegative screening testImpact of screeningFuture confirmatory studiesEmpiric therapyNew onsetLung donorsCenter experienceDonor testingUrine cultureLavage cultureMental statusAntimicrobial therapyTransplantPatientsScreening test