2019
Sex-Based Differences in Presentation, Treatment, and Complications Among Older Adults Hospitalized for Acute Myocardial Infarction
Nanna MG, Hajduk AM, Krumholz HM, Murphy TE, Dreyer RP, Alexander KP, Geda M, Tsang S, Welty FK, Safdar B, Lakshminarayan DK, Chaudhry SI, Dodson JA. Sex-Based Differences in Presentation, Treatment, and Complications Among Older Adults Hospitalized for Acute Myocardial Infarction. Circulation Cardiovascular Quality And Outcomes 2019, 12: e005691. PMID: 31607145, PMCID: PMC6913190, DOI: 10.1161/circoutcomes.119.005691.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overComorbidityDisability EvaluationFemaleHealth Status DisparitiesHealthcare DisparitiesHumansLife StyleMaleMyocardial RevascularizationNon-ST Elevated Myocardial InfarctionPatient AdmissionPrevalenceProspective StudiesRisk AssessmentRisk FactorsSex FactorsSocial Determinants of HealthST Elevation Myocardial InfarctionTime FactorsTreatment OutcomeUnited StatesConceptsAcute myocardial infarctionSex-based differencesPercutaneous coronary interventionFunctional impairmentOlder adultsHospital complicationsCoronary interventionOlder patientsCoronary diseaseMyocardial infarctionAge-related functional impairmentsAge-associated functional impairmentsLower ratesPrior coronary diseaseObstructive coronary diseaseProspective observational studyNSTEMI subgroupSTEMI subgroupUnderwent revascularizationAcute myocardialChest painClinical presentationAMI subgroupRisk factorsHigh prevalenceThirty-Day Readmission Risk Model for Older Adults Hospitalized With Acute Myocardial Infarction
Dodson JA, Hajduk AM, Murphy TE, Geda M, Krumholz HM, Tsang S, Nanna MG, Tinetti ME, Goldstein D, Forman DE, Alexander KP, Gill TM, Chaudhry SI. Thirty-Day Readmission Risk Model for Older Adults Hospitalized With Acute Myocardial Infarction. Circulation Cardiovascular Quality And Outcomes 2019, 12: e005320. PMID: 31010300, PMCID: PMC6481309, DOI: 10.1161/circoutcomes.118.005320.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overFemaleGeriatric AssessmentHealth Status IndicatorsHumansMaleMyocardial InfarctionPatient AdmissionPatient ReadmissionPredictive Value of TestsProspective StudiesReproducibility of ResultsRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesConceptsAcute myocardial infarctionReadmission risk modelFinal risk modelFunctional mobilityFunctional impairmentMyocardial infarctionOlder adultsFirst diastolic blood pressureChronic obstructive pulmonary diseaseAge-related functional impairmentsP2Y12 inhibitor useAcute kidney injuryDaily living (ADL) disabilityPatient-level factorsProspective cohort studyDiastolic blood pressureObstructive pulmonary diseasePatients of ageGeneral health statusStrongest predictorRisk modelMore comorbiditiesCause readmissionKidney injuryCohort study
2018
The Association of Frailty With In-Hospital Bleeding Among Older Adults With Acute Myocardial Infarction Insights From the ACTION Registry
Dodson JA, Hochman JS, Roe MT, Chen AY, Chaudhry SI, Katz S, Zhong H, Radford MJ, Udell J, Bagai A, Fonarow GC, Gulati M, Enriquez JR, Garratt KN, Alexander KP. The Association of Frailty With In-Hospital Bleeding Among Older Adults With Acute Myocardial Infarction Insights From the ACTION Registry. JACC Cardiovascular Interventions 2018, 11: 2287-2296. PMID: 30466828, PMCID: PMC6260951, DOI: 10.1016/j.jcin.2018.08.028.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAgedAged, 80 and overCardiac CatheterizationCognitionFemaleFrail ElderlyFrailtyGeriatric AssessmentHemorrhageHumansInpatientsMaleMobility LimitationMyocardial InfarctionPatient AdmissionPercutaneous Coronary InterventionRegistriesRisk AssessmentRisk FactorsTreatment OutcomeUnited StatesWalkingConceptsAssociation of frailtyAcute myocardial infarctionFrail patientsMajor bleedingCardiac catheterizationAMI patientsACTION RegistryAcute Myocardial Infarction—InsightsOlder adultsCategories of frailtyIn-Hospital BleedingNon-frail groupMultivariable logistic regressionYears of ageFrailty categoriesNonfrail patientsMyocardial infarctionIndependent associationCommon syndromeDaily livingHigh riskClinical strategiesPatientsBleedingFrailty
2017
Prehospital Delay in Older Adults with Acute Myocardial Infarction: The ComprehenSIVe Evaluation of Risk Factors in Older Patients with Acute Myocardial Infarction Study
Ouellet GM, Geda M, Murphy TE, Tsang S, Tinetti ME, Chaudhry SI. Prehospital Delay in Older Adults with Acute Myocardial Infarction: The ComprehenSIVe Evaluation of Risk Factors in Older Patients with Acute Myocardial Infarction Study. Journal Of The American Geriatrics Society 2017, 65: 2391-2396. PMID: 29044463, PMCID: PMC5681402, DOI: 10.1111/jgs.15102.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionAcute Myocardial Infarction StudyMyocardial Infarction StudyPrehospital delayOlder adultsOlder patientsHeart failureMyocardial infarctionRisk factorsFuture public health effortsContemporary national cohortMedical record abstractionPublic health effortsCross-sectional analysisAntiischemic therapyHospital presentationIndex hospitalizationHospital delaySymptom durationDiabetes mellitusClinical presentationComorbid conditionsRecord abstractionAtypical symptomsNonwhite race
2016
Restricting Symptoms Before and After Admission to Hospice
Cheraghlou S, Gahbauer EA, Leo-Summers L, Stabenau HF, Chaudhry SI, Gill TM. Restricting Symptoms Before and After Admission to Hospice. The American Journal Of Medicine 2016, 129: 754.e7-754.e15. PMID: 26968471, PMCID: PMC4914433, DOI: 10.1016/j.amjmed.2016.02.017.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAgedAged, 80 and overChest PainCognitive DysfunctionCohort StudiesDepressionDiarrheaDizzinessDyspneaEdemaFatigueFemaleHospice CareHospicesHumansIndependent LivingLongitudinal StudiesMaleMemory DisordersMuscle WeaknessMusculoskeletal PainNauseaPatient AdmissionPrevalenceProspective StudiesSleep Wake DisordersUnited StatesUrologic DiseasesVision DisordersVomitingConceptsHospice admissionEnd of lifeDistressing symptomsMean numberCommunity-dwelling older personsMonthly telephone interviewsOngoing cohort studyMonths of lifeEffect of hospiceHospice treatmentAdmission diagnosisEarly referralMedian durationCohort studySymptom prevalenceSuch symptomsSymptom increasesAdmissionPsychological symptomsSymptomsOlder personsRestricted activityHospiceTelephone interviewsPrevalence
2015
Association of Discharge Summary Quality With Readmission Risk for Patients Hospitalized With Heart Failure Exacerbation
Salim Al-Damluji M, Dzara K, Hodshon B, Punnanithinont N, Krumholz HM, Chaudhry SI, Horwitz LI. Association of Discharge Summary Quality With Readmission Risk for Patients Hospitalized With Heart Failure Exacerbation. Circulation Cardiovascular Quality And Outcomes 2015, 8: 109-111. PMID: 25587092, PMCID: PMC4303529, DOI: 10.1161/circoutcomes.114.001476.Peer-Reviewed Original Research