2018
The Association of Frailty With In-Hospital Bleeding Among Older Adults With Acute Myocardial Infarction Insights From the ACTION Registry
Dodson JA, Hochman JS, Roe MT, Chen AY, Chaudhry SI, Katz S, Zhong H, Radford MJ, Udell J, Bagai A, Fonarow GC, Gulati M, Enriquez JR, Garratt KN, Alexander KP. The Association of Frailty With In-Hospital Bleeding Among Older Adults With Acute Myocardial Infarction Insights From the ACTION Registry. JACC Cardiovascular Interventions 2018, 11: 2287-2296. PMID: 30466828, PMCID: PMC6260951, DOI: 10.1016/j.jcin.2018.08.028.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAgedAged, 80 and overCardiac CatheterizationCognitionFemaleFrail ElderlyFrailtyGeriatric AssessmentHemorrhageHumansInpatientsMaleMobility LimitationMyocardial InfarctionPatient AdmissionPercutaneous Coronary InterventionRegistriesRisk AssessmentRisk FactorsTreatment OutcomeUnited StatesWalkingConceptsAssociation of frailtyAcute myocardial infarctionFrail patientsMajor bleedingCardiac catheterizationAMI patientsACTION RegistryAcute Myocardial Infarction—InsightsOlder adultsCategories of frailtyIn-Hospital BleedingNon-frail groupMultivariable logistic regressionYears of ageFrailty categoriesNonfrail patientsMyocardial infarctionIndependent associationCommon syndromeDaily livingHigh riskClinical strategiesPatientsBleedingFrailty
2016
Slow Gait Speed and Risk of Mortality or Hospital Readmission After Myocardial Infarction in the Translational Research Investigating Underlying Disparities in Recovery from Acute Myocardial Infarction: Patients' Health Status Registry
Dodson JA, Arnold SV, Gosch KL, Gill TM, Spertus JA, Krumholz HM, Rich MW, Chaudhry SI, Forman DE, Masoudi FA, Alexander KP. Slow Gait Speed and Risk of Mortality or Hospital Readmission After Myocardial Infarction in the Translational Research Investigating Underlying Disparities in Recovery from Acute Myocardial Infarction: Patients' Health Status Registry. Journal Of The American Geriatrics Society 2016, 64: 596-601. PMID: 26926309, PMCID: PMC4803531, DOI: 10.1111/jgs.14016.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMyocardial infarctionSlow gaitHospital readmissionGait speedOlder adultsCox proportional hazards regressionMarker of frailtySlow gait speedTranslational researchProportional hazards regressionOutcomes 1 yearRisk of mortalityAssessment 1 monthBaseline characteristicsObservational cohortClinical factorsDiabetes mellitusHeart failureHazards regressionPrognostic importancePrognostic valueHigh prevalenceInfarctionReadmission
2014
Procedure timing as a predictor of inhospital adverse outcomes from implantable cardioverter-defibrillator implantation: Insights from the National Cardiovascular Data Registry
Hsu JC, Varosy PD, Parzynski CS, Chaudhry SI, Dewland TA, Curtis JP, Marcus GM. Procedure timing as a predictor of inhospital adverse outcomes from implantable cardioverter-defibrillator implantation: Insights from the National Cardiovascular Data Registry. American Heart Journal 2014, 169: 45-52.e3. PMID: 25497247, DOI: 10.1016/j.ahj.2014.10.006.Peer-Reviewed Original ResearchConceptsHospital stayAdverse eventsICD recipientsWeekends/holidaysInhospital deathGreater oddsNational Cardiovascular Data Registry ICD RegistryFirst-time ICD recipientsImplantable cardioverter defibrillator implantationNational Cardiovascular Data RegistryImplantable cardioverter-defibrillator (ICD) proceduresImplantable cardioverter defibrillator recipientsHierarchical multivariable logistic regressionInhospital adverse outcomesCardioverter-defibrillator implantationProlonged hospital stayMultivariable logistic regressionReal-world populationAfternoon/eveningTotal complicationsMultivariable adjustmentAdverse outcomesHospital characteristicsICD implantsData registry
2013
Lower Hospital Volume Is Associated With Higher In-Hospital Mortality in Patients Undergoing Primary Percutaneous Coronary Intervention for ST-Segment–Elevation Myocardial Infarction
Kontos MC, Wang Y, Chaudhry SI, Vetrovec GW, Curtis J, Messenger J. Lower Hospital Volume Is Associated With Higher In-Hospital Mortality in Patients Undergoing Primary Percutaneous Coronary Intervention for ST-Segment–Elevation Myocardial Infarction. Circulation Cardiovascular Quality And Outcomes 2013, 6: 659-667. PMID: 24192572, DOI: 10.1161/circoutcomes.113.000233.Peer-Reviewed Original ResearchConceptsPrimary percutaneous coronary interventionPrimary PCIHigh-volume hospitalsLow-volume hospitalsPercutaneous coronary interventionBalloon timeCoronary interventionHospital volumeHigher annual hospital volumeHigher In-Hospital MortalityAnnual hospital volumeLow hospital volumeRoutine coronary stentingIn-Hospital MortalityElevation myocardial infarctionMajority of patientsNew pharmacological agentsHospital mortalityCathPCI RegistryMultivariate adjustmentUnadjusted mortalityCoronary stentingMyocardial infarctionCurrent guidelinesPatient visitsUse of Remote Monitoring of Newly Implanted Cardioverter-Defibrillators
Akar JG, Bao H, Jones P, Wang Y, Chaudhry SI, Varosy P, Masoudi FA, Stein K, Saxon LA, Curtis JP. Use of Remote Monitoring of Newly Implanted Cardioverter-Defibrillators. Circulation 2013, 128: 2372-2383. PMID: 24043302, DOI: 10.1161/circulationaha.113.002481.Peer-Reviewed Original ResearchConceptsMedian odds ratioOdds ratioNational Cardiovascular Data Registry ICD RegistryRemote patient monitoringMultivariable logistic regressionHealth-related factorsImplanted cardioverter defibrillatorEligible patientsICD RegistryLack of enrollmentCurrent guidelinesCardioverter defibrillatorPatientsLogistic regressionLocal practice environmentMajor causeHealth insuranceSubsequent activationEnrollmentPractice environmentPatient monitoringPhysiciansActivationRPM systemSuccessful use
2012
Bleeding-Avoidance Strategies and Outcomes in Patients ≥80 Years of Age With ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention (from the NCDR CathPCI Registry)
Dodson JA, Wang Y, Chaudhry SI, Curtis JP. Bleeding-Avoidance Strategies and Outcomes in Patients ≥80 Years of Age With ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention (from the NCDR CathPCI Registry). The American Journal Of Cardiology 2012, 110: 1-6. PMID: 22475362, PMCID: PMC3666171, DOI: 10.1016/j.amjcard.2012.02.039.Peer-Reviewed Original ResearchConceptsPrimary percutaneous coronary interventionPrimary PCIBleeding-avoidance strategiesST-segment elevation myocardial infarctionElevation myocardial infarctionPercutaneous coronary interventionMyocardial infarctionCoronary interventionUndergoing primary percutaneous coronary interventionST-elevation myocardial infarctionDirect thrombin inhibitorVascular closure deviceYears of ageBleeding complicationsCathPCI RegistryMultivariable analysisRadial accessClosure deviceHigh riskBleedingPatientsThrombin inhibitorsInfarctionLow bleedingStudy period