2020
Risk Model for Decline in Activities of Daily Living Among Older Adults Hospitalized With Acute Myocardial Infarction: The SILVER‐AMI Study
Hajduk AM, Dodson JA, Murphy TE, Tsang S, Geda M, Ouellet GM, Gill TM, Brush JE, Chaudhry SI. Risk Model for Decline in Activities of Daily Living Among Older Adults Hospitalized With Acute Myocardial Infarction: The SILVER‐AMI Study. Journal Of The American Heart Association 2020, 9: e015555. PMID: 33000681, PMCID: PMC7792390, DOI: 10.1161/jaha.119.015555.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionDaily living declineSILVER-AMI StudyDaily livingOlder patientsMonths postdischargeMyocardial infarctionFunctional declineImportant patient-centered outcomesPoor long-term outcomesLonger hospital stayLong-term outcomesPatient-centered outcomesGeriatric impairmentsHospital stayAMI survivorsClinical variablesMean ageMedical recordsRisk factorsRestorative therapyPhysical activityAMI hospitalizationPsychosocial factorsUS hospitalsThe Association Between Hospital End-of-Life Care Quality and the Care Received Among Patients With Heart Failure
Feder SL, Tate J, Ersek M, Krishnan S, Chaudhry SI, Bastian LA, Rolnick J, Kutney-Lee A, Akgün KM. The Association Between Hospital End-of-Life Care Quality and the Care Received Among Patients With Heart Failure. Journal Of Pain And Symptom Management 2020, 61: 713-722.e1. PMID: 32931904, PMCID: PMC7952458, DOI: 10.1016/j.jpainsymman.2020.09.006.Peer-Reviewed Original ResearchConceptsHeart failure patientsPalliative care consultationVeterans Health AdministrationLife care qualityFailure patientsHeart failureCare consultationsHighest quintileVA hospitalsIntensive care unit deathCare qualityIntensive care unitHealth care systemCare unitInpatient hospiceMean ageLowest quintileHospital endRetrospective analysisHOSPITAL scorePatientsHealth AdministrationCare processesHospitalLogistic regression
2019
Predicting 6-Month Mortality for Older Adults Hospitalized With Acute Myocardial Infarction: A Cohort Study.
Dodson JA, Hajduk AM, Geda M, Krumholz HM, Murphy TE, Tsang S, Tinetti ME, Nanna MG, McNamara R, Gill TM, Chaudhry SI. Predicting 6-Month Mortality for Older Adults Hospitalized With Acute Myocardial Infarction: A Cohort Study. Annals Of Internal Medicine 2019, 172: 12-21. PMID: 31816630, PMCID: PMC7695040, DOI: 10.7326/m19-0974.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionPost-AMI mortalityFunctional impairmentOlder adultsCohort studyMean ageMyocardial infarctionPatient-reported health statusNet reclassification improvement indexProspective cohort studyParticipants' mean ageFinal risk modelMobility impairmentsGood discriminatory abilityRisk modelChart reviewHospital dischargePrognostic utilityBlood InstituteClinical variablesNational HeartHigh prevalenceHealth statusMortalityYounger counterpartsAssociation Between Mobility Measured During Hospitalization and Functional Outcomes in Older Adults With Acute Myocardial Infarction in the SILVER-AMI Study
Hajduk AM, Murphy TE, Geda ME, Dodson JA, Tsang S, Haghighat L, Tinetti ME, Gill TM, Chaudhry SI. Association Between Mobility Measured During Hospitalization and Functional Outcomes in Older Adults With Acute Myocardial Infarction in the SILVER-AMI Study. JAMA Internal Medicine 2019, 179: 1669-1677. PMID: 31589285, PMCID: PMC6784755, DOI: 10.1001/jamainternmed.2019.4114.Peer-Reviewed Original ResearchAcute myocardial infarctionFunctional declineModerate impairmentMild impairmentSevere impairmentOlder patientsADL declineMyocardial infarctionRisk markersMobility impairmentsOlder survivorsAMI hospitalizationMultivariable-adjusted logistic regressionImportant patient-centered outcomesOlder adultsProspective cohort studyPatient-centered outcomesSelf-reported functionSILVER-AMI StudyPotent risk markerPercent of participantsCohort studyPrimary outcomeMean ageFunctional outcomeUsefulness of Social Support in Older Adults After Hospitalization for Acute Myocardial Infarction (from the SILVER-AMI Study)
Green YS, Hajduk AM, Song X, Krumholz HM, Sinha SK, Chaudhry SI. Usefulness of Social Support in Older Adults After Hospitalization for Acute Myocardial Infarction (from the SILVER-AMI Study). The American Journal Of Cardiology 2019, 125: 313-319. PMID: 31787249, PMCID: PMC7003680, DOI: 10.1016/j.amjcard.2019.10.038.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionPost-AMI outcomesMyocardial infarctionIndependent associationMedical Outcomes Study Social Support SurveySocial supportOlder AMI patientsSocial Support SurveyParticipants 75 yearsLow emotional supportLow social supportImportant social determinantInitial hospitalizationOlder patientsDevelopment of interventionsAMI patientsMultivariable analysisMean ageMultivariable regressionHealth outcomesSupport SurveyInformational supportReadmissionSocial determinantsOlder adultsAcute Kidney Injury Among Older Patients Undergoing Coronary Angiography for Acute Myocardial Infarction: The SILVER-AMI Study
Dodson JA, Hajduk A, Curtis J, Geda M, Krumholz HM, Song X, Tsang S, Blaum C, Miller P, Parikh CR, Chaudhry SI. Acute Kidney Injury Among Older Patients Undergoing Coronary Angiography for Acute Myocardial Infarction: The SILVER-AMI Study. The American Journal Of Medicine 2019, 132: e817-e826. PMID: 31170374, PMCID: PMC6891160, DOI: 10.1016/j.amjmed.2019.05.022.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAcute Kidney InjuryAge FactorsAgedAged, 80 and overCohort StudiesCoronary AngiographyDatabases, FactualFemaleGeriatric AssessmentHospital MortalityHospitalizationHumansKaplan-Meier EstimateLogistic ModelsMaleMyocardial InfarctionOdds RatioPrognosisProportional Hazards ModelsRisk AssessmentSeverity of Illness IndexSurvival AnalysisConceptsAcute kidney injuryAcute myocardial infarctionAge-related conditionsKidney injuryBody mass indexCoronary angiographyRisk factorsMyocardial infarctionOlder patientsMean ageAcute kidney injury risk factorsAcute Myocardial Infarction StudyAcute myocardial infarction cohortOlder adultsGlobal Outcomes criteriaMyocardial Infarction StudyInjury risk factorsParticipants' mean ageSILVER-AMI StudyMultivariable adjustmentComorbid diseasesHeart failureIndependent predictorsGeriatric conditionsMass index
2015
Burden of Comorbidities and Functional and Cognitive Impairments in Elderly Patients at the Initial Diagnosis of Heart Failure and Their Impact on Total Mortality The Cardiovascular Health Study
Murad K, Goff DC, Morgan TM, Burke GL, Bartz TM, Kizer JR, Chaudhry SI, Gottdiener JS, Kitzman DW. Burden of Comorbidities and Functional and Cognitive Impairments in Elderly Patients at the Initial Diagnosis of Heart Failure and Their Impact on Total Mortality The Cardiovascular Health Study. JACC Heart Failure 2015, 3: 542-550. PMID: 26160370, PMCID: PMC4499113, DOI: 10.1016/j.jchf.2015.03.004.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAgedAged, 80 and overAtrial FibrillationCognition DisordersCohort StudiesComorbidityCoronary DiseaseFemaleHeart FailureHumansHypertensionIncidenceLongitudinal StudiesMalePeripheral Arterial DiseasePhysical FitnessPrevalenceProportional Hazards ModelsPulmonary Disease, Chronic ObstructiveConceptsIncident heart failureCardiovascular Health StudyHeart failureGreater mortality riskMortality riskPercent of participantsCognitive impairmentElderly patientsFunctional impairmentDaily livingHealth StudyBurden of comorbiditiesChronic kidney diseaseMultivariable-adjusted modelsTotal mortality riskRelevant comorbiditiesDiabetes mellitusInitial diagnosisCerebrovascular diseaseKidney diseaseMean ageHigh burdenComorbiditiesInstrumental activitiesMortality rate
2013
Restricting Symptoms in the Last Year of Life: A Prospective Cohort Study
Chaudhry SI, Murphy TE, Gahbauer E, Sussman LS, Allore HG, Gill TM. Restricting Symptoms in the Last Year of Life: A Prospective Cohort Study. JAMA Internal Medicine 2013, 173: 1534-1540. PMID: 23836056, PMCID: PMC4041035, DOI: 10.1001/jamainternmed.2013.8732.Peer-Reviewed Original ResearchConceptsProspective cohort studySymptom occurrenceCohort studyIndividuals 70 yearsGreater New HavenTime of deathOlder patientsSecondary outcomesSymptom burdenClinical factorsPrimary outcomeComorbid conditionsMultivariable analysisMean ageSudden deathMAIN OUTCOMEDichotomous outcomesPsychological symptomsSymptomsOlder personsMultimorbidityMonthly interviewsMonthsDeathMean numberCognitive Impairment in Older Adults with Heart Failure: Prevalence, Documentation, and Impact on Outcomes
Dodson JA, Truong TT, Towle VR, Kerins G, Chaudhry SI. Cognitive Impairment in Older Adults with Heart Failure: Prevalence, Documentation, and Impact on Outcomes. The American Journal Of Medicine 2013, 126: 120-126. PMID: 23331439, PMCID: PMC3553506, DOI: 10.1016/j.amjmed.2012.05.029.Peer-Reviewed Original ResearchConceptsHeart failureCognitive impairmentOlder adultsPhysician documentationSevere impairmentCox proportional hazards regressionFolstein Mini-Mental State ExaminationMini-Mental State ExaminationProportion of patientsProspective cohort studyTime of hospitalizationProportional hazards regressionTime of dischargeHospital discharge summariesYears of ageMild cognitive impairmentMultivariable adjustmentCohort studyHospital dischargeHospital readmissionHazards regressionMean agePrimary diagnosisState ExaminationPatients
2010
Geriatric Conditions and Subsequent Mortality in Older Patients With Heart Failure
Chaudhry SI, Wang Y, Gill TM, Krumholz HM. Geriatric Conditions and Subsequent Mortality in Older Patients With Heart Failure. Journal Of The American College Of Cardiology 2010, 55: 309-316. PMID: 20117435, PMCID: PMC2832791, DOI: 10.1016/j.jacc.2009.07.066.Peer-Reviewed Original ResearchConceptsLong-term mortalityGeriatric conditionsNet reclassification improvementMobility disabilityOlder patientsReclassification improvementRisk factorsMultivariable logistic regression modelHeart failure hospitalizationIndependent risk factorTraditional risk factorsMedical record dataFinal multivariable modelYears of ageLogistic regression modelsFailure hospitalizationTerm mortalityHeart failureIndependent predictorsPrognostic importanceMean ageMultivariable modelMedicare beneficiariesMortality rateSubsequent mortality