2006
Comparative immunohistological analysis of the Montenegro skin test reaction in asymptomatic infection and in acute and chronic cutaneous leishmaniasis
Guarín N, Palma G, Pirmez C, Valderrama L, Tovar R, Saravia NG. Comparative immunohistological analysis of the Montenegro skin test reaction in asymptomatic infection and in acute and chronic cutaneous leishmaniasis. Biomédica 2006, 26: 38-48. PMID: 17361840, DOI: 10.7705/biomedica.v26i1.1498.Peer-Reviewed Original ResearchConceptsSkin test reactionsMontenegro skin testSkin testChronic lesionsAcute lesionsAsymptomatic infectionT lymphocytesImmune responseB cellsComparative immunohistological analysisProportion of CD4Chronic cutaneous leishmaniasisType hypersensitivity reactionCellular immune responsesSkin test sitesTest reactionsLeishmaniasis lesionsCellular infiltrateHypersensitivity reactionsLeishmania infectionChronic diseasesInflammatory responseChronic patientsT cellsCutaneous leishmaniasis
1993
Epidemiology of Cutaneous Leishmaniasis in Colombia: A Longitudinal Study of the Natural History, Prevalence, and Incidence of Infection and Clinical Manifestations
Weigle K, Santrich C, Martinez F, Valderrama L, Saravia N. Epidemiology of Cutaneous Leishmaniasis in Colombia: A Longitudinal Study of the Natural History, Prevalence, and Incidence of Infection and Clinical Manifestations. The Journal Of Infectious Diseases 1993, 168: 699-708. PMID: 8354912, DOI: 10.1093/infdis/168.3.699.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAnimalsAntigens, ProtozoanChildChild, PreschoolCohort StudiesColombiaFemaleHumansIncidenceInfantInfant, NewbornLeishmania braziliensisLeishmaniasis, CutaneousLongitudinal StudiesMaleMiddle AgedModels, BiologicalProspective StudiesRespiratory SystemRural PopulationSex FactorsSkinSkin TestsTime FactorsConceptsLeishmanin skin test conversionMost primary infectionsSkin test conversionBurden of diseaseIncidence of infectionLeishmaniasis control programClinical manifestationsProspective studyPrimary infectionTest conversionLeishmania infectionIncidence rateTypical scarCutaneous leishmaniasisEndemic areasNew infectionsLeishmaniasis casesNatural historyInfectionLeishmaniasisNaive hostsLongitudinal studyLesionsOne-thirdIncidence
1991
Correlation between histopathology, immune response, clinical presentation, and evolution in Leishmania braziliensis infection.
Gutierrez Y, Salinas G, Palma G, Valderrama L, Santrich C, Saravia N. Correlation between histopathology, immune response, clinical presentation, and evolution in Leishmania braziliensis infection. American Journal Of Tropical Medicine And Hygiene 1991, 45: 281-9. PMID: 1928562, DOI: 10.4269/ajtmh.1991.45.281.Peer-Reviewed Original ResearchConceptsPresence of amastigotesImmune responseClinical presentationLeishmania-specific immune responseAbsence of amastigotesPresence of epithelioidLymphocyte transformation responsesPresence of granulomasRole of antibodiesCellular immune responsesPresence of eosinophilsSerum antibody titersLeishmania braziliensis infectionPresence of LeishmaniaLeishmanial lesionsBraziliensis infectionCellular infiltrateType hypersensitivityClinical parametersActive lesionsAntibody titersEvolution of diseaseSoluble mediatorsTegumentary leishmaniasisEpitheloid cellsLeishmanin skin test standardization and evaluation of safety, dose, storage, longevity of reaction and sensitization.
Weigle K, Valderrama L, Arias A, Santrich C, Saravia N. Leishmanin skin test standardization and evaluation of safety, dose, storage, longevity of reaction and sensitization. American Journal Of Tropical Medicine And Hygiene 1991, 44: 260-71. PMID: 2035747, DOI: 10.4269/ajtmh.1991.44.260.Peer-Reviewed Original Research