Recurrent lesions in human Leishmania braziliensis infection—reactivation or reinfection?
Saravia N, Segura I, Labrada L, Weigle K, Giannini S, Pacheco R, Goncalves A. Recurrent lesions in human Leishmania braziliensis infection—reactivation or reinfection? The Lancet 1990, 336: 398-402. PMID: 1974943, DOI: 10.1016/0140-6736(90)91945-7.Peer-Reviewed Original ResearchConceptsRecurrent lesionsInitial lesionLonger disease-free intervalDisease-free intervalAmerican tegumentary leishmaniasisRecurrent diseaseEndogenous reactivationExogenous reinfectionVaccination strategiesClinical dataPatientsTegumentary leishmaniasisLesionsTreatment evaluationRecurrent strainsLeishmania braziliensisIdentical strainsLatter groupReinfectionRestriction endonuclease analysisEndonuclease analysisStrain pairsMolecular karyotypingKaryotype profilePolymorphism