2008
Etiologic agent of an epidemic of cutaneous leishmaniasis in Tolima, Colombia.
Rodríguez-Barraquer I, Góngora R, Prager M, Pacheco R, Montero LM, Navas A, Ferro C, Miranda MC, Saravia NG. Etiologic agent of an epidemic of cutaneous leishmaniasis in Tolima, Colombia. American Journal Of Tropical Medicine And Hygiene 2008, 78: 276-82. PMID: 18256429, DOI: 10.4269/ajtmh.2008.78.276.Peer-Reviewed Original ResearchConceptsAmerican cutaneous leishmaniasisCutaneous leishmaniasisEtiologic agentLeishmania guyanensisProbable etiologic agentLeishmaniasis control programLarge epidemicsMonoclonal antibodiesLeishmania isolatesLeishmaniasisPeridomestic settingsZoonotic diseaseL. panamensisEpidemicDomestic transmissionControl programsPresent studyIsoenzyme electrophoresisIsolatesAgentsGuyanensisPatientsDiseaseDiagnosisAntibodies
2006
Resistance to Oxidative Stress Is Associated with Metastasis in Mucocutaneous Leishmaniasis
Acestor N, Masina S, Ives A, Walker J, Saravia NG, Fasel N. Resistance to Oxidative Stress Is Associated with Metastasis in Mucocutaneous Leishmaniasis. The Journal Of Infectious Diseases 2006, 194: 1160-1167. PMID: 16991092, DOI: 10.1086/507646.Peer-Reviewed Original ResearchConceptsMucocutaneous leishmaniasisMetastatic phenotypeMetastatic diseaseCutaneous lesionsMicrobicidal responsesMetastatic disseminationGolden hamstersNasopharyngeal tissuesCytoplasmic peroxiredoxinOxidative stressLeishmania promastigotesNonmetastatic clonesL. panamensisLeishmaniasisHost cellsParasitesPhenotypePatientsMetastasisHeat shockPathogenesisLesionsPeroxidase activityDiseaseDissemination
1993
Leishmania (Viannia) panamensis-specific IgE and IgA antibodies in relation to expression of human tegumentary leishmaniasis.
O'Neil C, Labrada M, Saravia N. Leishmania (Viannia) panamensis-specific IgE and IgA antibodies in relation to expression of human tegumentary leishmaniasis. American Journal Of Tropical Medicine And Hygiene 1993, 49: 181-8. PMID: 8357080, DOI: 10.4269/ajtmh.1993.49.181.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAnimalsAntibodies, ProtozoanAntibody SpecificityAntigens, ProtozoanChildChild, PreschoolCross ReactionsDose-Response Relationship, ImmunologicEnzyme-Linked Immunosorbent AssayFemaleHumansImmunoglobulin AImmunoglobulin EInfantLeishmania braziliensisLeishmaniasis, CutaneousLeishmaniasis, MucocutaneousMaleRadioallergosorbent TestRetrospective StudiesConceptsAmerican tegumentary leishmaniasisIgA antibodiesEnzyme-linked immunosorbent assayTegumentary leishmaniasisRadioallergosorbent testRAST valuesHuman tegumentary leishmaniasisDuration of diseaseIgA levelsMucocutaneous diseaseBiopsy specimenBiopsy specimensCutaneous diseaseSevere formPatientsHeterologous antigensDisease evolutionIgEImmunosorbent assayElevated levelsLeishmaniasisDiseaseInhibition testingAntibodiesSeparate groups
1990
Mucosal disease caused by Leishmania braziliensis guyanensis.
Santrich C, Segura I, Arias A, Saravia N. Mucosal disease caused by Leishmania braziliensis guyanensis. American Journal Of Tropical Medicine And Hygiene 1990, 42: 51-5. PMID: 2301705, DOI: 10.4269/ajtmh.1990.42.51.Peer-Reviewed Original Research