Sequencing of Sclerosing Microcystic Adenocarcinoma Identifies Mutational Burden and Somatic Variants Associated With Tumorigenesis
JIANG R, MARQUEZ J, TOWER JI, JACOBS D, CHEN W, MEHRA S, PRASAD ML, JUDSON BL. Sequencing of Sclerosing Microcystic Adenocarcinoma Identifies Mutational Burden and Somatic Variants Associated With Tumorigenesis. Anticancer Research 2020, 40: 6375-6379. PMID: 33109575, DOI: 10.21873/anticanres.14658.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdenomaAdultCarcinogenesisCyclin-Dependent KinasesExome SequencingFemaleGene Expression Regulation, NeoplasticHumansMouthMutationNeoplasmsConceptsMicrocystic adnexal carcinomaMutational burdenContext of immunosuppressionOral cavity neoplasiaCases of SMADiagnosis of SMAWhole-exome sequencingPotential molecular mechanismsImmunosuppression therapyNodal diseaseNeck dissectionPsoriatic arthritisResidual tumorAdnexal carcinomaPartial glossectomyTongue massSomatic variantsMicrocystic adenocarcinomaSMA casesExome sequencingGenomic profilesFunction mutationsTumorigenesisBurdenMolecular mechanisms